MALDI Guided SpatialOMx (R) Uncovers Proteomic Profiles in Tumor Subpopulations of Breast Cancer

Janina Oetjen; Romano Hebeler; Frederic Dewez; Corinna Henkel; Benjamin Balluff; Ron Heeren

MALDI Guided SpatialOMx (R) Uncovers Proteomic Profiles in Tumor Subpopulations of Breast Cancer

Janina Oetjen^*, Romano Hebeler, Frederic Dewez, Corinna Henkel, Benjamin Balluff, Ron Heeren

^*Corresponding author for this work

Research output: Contribution to journal › Editorial › Academic › peer-review

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Abstract

The timsTOF fleX system bridges a current gap by providing MALDI Imaging and in-depth proteomics analysis in just one instrument. The instrument offers all benefits of a timsTOF Pro for time-efficient and sensitive proteomics, combined with a high-resolution MALDI source and stage. Using PASEF technology, it is possible to retrieve high protein ID rates with small sample amounts. Here we present the new SpatialOMx (R) workflow to identify distinct proteomic profiles for different tumor subpopulations in breast cancer as an example for this powerful approach.

Original language	English
Pages (from-to)	528-530
Number of pages	3
Journal	Lc Gc North America
Volume	38
Issue number	9
Publication status	Published - Sept 2020

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title = "MALDI Guided SpatialOMx (R) Uncovers Proteomic Profiles in Tumor Subpopulations of Breast Cancer",

abstract = "The timsTOF fleX system bridges a current gap by providing MALDI Imaging and in-depth proteomics analysis in just one instrument. The instrument offers all benefits of a timsTOF Pro for time-efficient and sensitive proteomics, combined with a high-resolution MALDI source and stage. Using PASEF technology, it is possible to retrieve high protein ID rates with small sample amounts. Here we present the new SpatialOMx (R) workflow to identify distinct proteomic profiles for different tumor subpopulations in breast cancer as an example for this powerful approach.",

author = "Janina Oetjen and Romano Hebeler and Frederic Dewez and Corinna Henkel and Benjamin Balluff and Ron Heeren",

year = "2020",

month = sep,

language = "English",

volume = "38",

pages = "528--530",

journal = "Lc Gc North America",

issn = "1527-5949",

publisher = "Advanstar Communications",

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TY - JOUR

T1 - MALDI Guided SpatialOMx (R) Uncovers Proteomic Profiles in Tumor Subpopulations of Breast Cancer

AU - Oetjen, Janina

AU - Hebeler, Romano

AU - Dewez, Frederic

AU - Henkel, Corinna

AU - Balluff, Benjamin

AU - Heeren, Ron

PY - 2020/9

Y1 - 2020/9

N2 - The timsTOF fleX system bridges a current gap by providing MALDI Imaging and in-depth proteomics analysis in just one instrument. The instrument offers all benefits of a timsTOF Pro for time-efficient and sensitive proteomics, combined with a high-resolution MALDI source and stage. Using PASEF technology, it is possible to retrieve high protein ID rates with small sample amounts. Here we present the new SpatialOMx (R) workflow to identify distinct proteomic profiles for different tumor subpopulations in breast cancer as an example for this powerful approach.

AB - The timsTOF fleX system bridges a current gap by providing MALDI Imaging and in-depth proteomics analysis in just one instrument. The instrument offers all benefits of a timsTOF Pro for time-efficient and sensitive proteomics, combined with a high-resolution MALDI source and stage. Using PASEF technology, it is possible to retrieve high protein ID rates with small sample amounts. Here we present the new SpatialOMx (R) workflow to identify distinct proteomic profiles for different tumor subpopulations in breast cancer as an example for this powerful approach.

M3 - Editorial

SN - 1527-5949

VL - 38

SP - 528

EP - 530

JO - Lc Gc North America

JF - Lc Gc North America

IS - 9

ER -