Machine-learning model derived gene signature predictive of paclitaxel survival benefit in gastric cancer: results from the randomised phase III SAMIT trial

R. Sundar; N.B. Kumarakulasinghe; Y.H. Chan; K. Yoshida; T. Yoshikawa; Y. Miyagi; Y. Rino; M. Masuda; J. Guan; J. Sakamoto; S. Tanaka; A.L.K. Tan; M.M. Hoppe; A.D. Jeyasekharan; C.C.Y. Ng; M. De Simone; H.I. Grabsch; J. Lee; T. Oshima; A. Tsuburaya; P. Tan

doi:10.1136/gutjnl-2021-324060

Machine-learning model derived gene signature predictive of paclitaxel survival benefit in gastric cancer: results from the randomised phase III SAMIT trial

R. Sundar, N.B. Kumarakulasinghe, Y.H. Chan, K. Yoshida, T. Yoshikawa, Y. Miyagi, Y. Rino, M. Masuda, J. Guan, J. Sakamoto, S. Tanaka, A.L.K. Tan^*, M.M. Hoppe, A.D. Jeyasekharan, C.C.Y. Ng, M. De Simone, H.I. Grabsch, J. Lee, T. Oshima^*, A. Tsuburaya^*P. Tan^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

4 Citations (Web of Science)

Original language	English
Number of pages	10
Journal	Gut
DOIs	https://doi.org/10.1136/gutjnl-2021-324060
Publication status	E-pub ahead of print - 11 May 2021

Keywords

gastric cancer
chemotherapy
adjuvant treatment
COMPREHENSIVE MOLECULAR CHARACTERIZATION
CISPLATIN
CHEMOTHERAPY
5-FLUOROURACIL
SENSITIVITY
DOCETAXEL
THERAPY
FAMILY
TUMORS
UFT

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Sundar, R., Kumarakulasinghe, N. B., Chan, Y. H., Yoshida, K., Yoshikawa, T., Miyagi, Y., Rino, Y., Masuda, M., Guan, J., Sakamoto, J., Tanaka, S., Tan, A. L. K., Hoppe, M. M., Jeyasekharan, A. D., Ng, C. C. Y., De Simone, M., Grabsch, H. I., Lee, J., Oshima, T., ... Tan, P. (2021). Machine-learning model derived gene signature predictive of paclitaxel survival benefit in gastric cancer: results from the randomised phase III SAMIT trial. Gut. https://doi.org/10.1136/gutjnl-2021-324060

Sundar, R. ; Kumarakulasinghe, N.B. ; Chan, Y.H. ; Yoshida, K. ; Yoshikawa, T. ; Miyagi, Y. ; Rino, Y. ; Masuda, M. ; Guan, J. ; Sakamoto, J. ; Tanaka, S. ; Tan, A.L.K. ; Hoppe, M.M. ; Jeyasekharan, A.D. ; Ng, C.C.Y. ; De Simone, M. ; Grabsch, H.I. ; Lee, J. ; Oshima, T. ; Tsuburaya, A. ; Tan, P. / Machine-learning model derived gene signature predictive of paclitaxel survival benefit in gastric cancer: results from the randomised phase III SAMIT trial. In: Gut. 2021.

@article{6a5a8f1ac0104b328af8d2df41f63c74,

title = "Machine-learning model derived gene signature predictive of paclitaxel survival benefit in gastric cancer: results from the randomised phase III SAMIT trial",

keywords = "gastric cancer, chemotherapy, adjuvant treatment, COMPREHENSIVE MOLECULAR CHARACTERIZATION, CISPLATIN, CHEMOTHERAPY, 5-FLUOROURACIL, SENSITIVITY, DOCETAXEL, THERAPY, FAMILY, TUMORS, UFT",

author = "R. Sundar and N.B. Kumarakulasinghe and Y.H. Chan and K. Yoshida and T. Yoshikawa and Y. Miyagi and Y. Rino and M. Masuda and J. Guan and J. Sakamoto and S. Tanaka and A.L.K. Tan and M.M. Hoppe and A.D. Jeyasekharan and C.C.Y. Ng and {De Simone}, M. and H.I. Grabsch and J. Lee and T. Oshima and A. Tsuburaya and P. Tan",

year = "2021",

month = may,

day = "11",

doi = "10.1136/gutjnl-2021-324060",

language = "English",

journal = "Gut",

issn = "0017-5749",

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Sundar, R, Kumarakulasinghe, NB, Chan, YH, Yoshida, K, Yoshikawa, T, Miyagi, Y, Rino, Y, Masuda, M, Guan, J, Sakamoto, J, Tanaka, S, Tan, ALK, Hoppe, MM, Jeyasekharan, AD, Ng, CCY, De Simone, M, Grabsch, HI, Lee, J, Oshima, T, Tsuburaya, A & Tan, P 2021, 'Machine-learning model derived gene signature predictive of paclitaxel survival benefit in gastric cancer: results from the randomised phase III SAMIT trial', Gut. https://doi.org/10.1136/gutjnl-2021-324060

Machine-learning model derived gene signature predictive of paclitaxel survival benefit in gastric cancer: results from the randomised phase III SAMIT trial. / Sundar, R.; Kumarakulasinghe, N.B.; Chan, Y.H.; Yoshida, K.; Yoshikawa, T.; Miyagi, Y.; Rino, Y.; Masuda, M.; Guan, J.; Sakamoto, J.; Tanaka, S.; Tan, A.L.K.; Hoppe, M.M.; Jeyasekharan, A.D.; Ng, C.C.Y.; De Simone, M.; Grabsch, H.I.; Lee, J.; Oshima, T.; Tsuburaya, A.; Tan, P.

In: Gut, 11.05.2021.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Machine-learning model derived gene signature predictive of paclitaxel survival benefit in gastric cancer: results from the randomised phase III SAMIT trial

AU - Sundar, R.

AU - Kumarakulasinghe, N.B.

AU - Chan, Y.H.

AU - Yoshida, K.

AU - Yoshikawa, T.

AU - Miyagi, Y.

AU - Rino, Y.

AU - Masuda, M.

AU - Guan, J.

AU - Sakamoto, J.

AU - Tanaka, S.

AU - Tan, A.L.K.

AU - Hoppe, M.M.

AU - Jeyasekharan, A.D.

AU - Ng, C.C.Y.

AU - De Simone, M.

AU - Grabsch, H.I.

AU - Lee, J.

AU - Oshima, T.

AU - Tsuburaya, A.

AU - Tan, P.

PY - 2021/5/11

Y1 - 2021/5/11

KW - gastric cancer

KW - chemotherapy

KW - adjuvant treatment

KW - COMPREHENSIVE MOLECULAR CHARACTERIZATION

KW - CISPLATIN

KW - CHEMOTHERAPY

KW - 5-FLUOROURACIL

KW - SENSITIVITY

KW - DOCETAXEL

KW - THERAPY

KW - FAMILY

KW - TUMORS

KW - UFT

U2 - 10.1136/gutjnl-2021-324060

DO - 10.1136/gutjnl-2021-324060

M3 - Article

C2 - 33980610

JO - Gut

JF - Gut

SN - 0017-5749

ER -