TY - JOUR
T1 - Low-Level Laser Therapy and Topical Medications for Treating Aphthous Ulcers
T2 - A Systematic Review
AU - Ahmed, Mohammed Khaleel
AU - Jafer, Mohammed
AU - Nayeem, Maryam
AU - Moafa, Ibtisam Hussain
AU - Quadri, Mir Furruq Ali
AU - Gopalaiah, Hema
AU - Quadri, Mir Faeq Ali
N1 - Publisher Copyright:
© 2020 Khaleel Ahmed et al.
PY - 2020
Y1 - 2020
N2 - Objective: The study compares low-level laser therapy with topical medications for treating aphthous ulcers.Methods: A search of articles in this systematic review was completed in six databases. Treatment and comparative groups comprised of patients subjected to laser therapy and topical medications, respectively. Two different treatment outcomes were considered; pain and size of the lesion. Risk of bias was assessed using the Revised Cochrane risk-of-bias tool for randomized trials.Results: From 109 articles, five randomized control trials fulfilled the selection criteria. The overall sample comprised of 98 males and 232 females, with a mean age of 32.4 years. The laser therapies in each included study had different active media and varying wavelengths. Topical medication used in the comparative group were triamcinolone acetonide, amlexanox, granofurin, and solcoseryl. Findings showed that patients who reported lower pain and decreased aphthous ulcer lesions were more in the laser therapy group than in the topical medication group.Conclusion: Low-level laser therapy was better in treating aphthous ulcer lesions in comparison to topical medications, and all laser wavelengths in the included reports were seen to be effective. However, the results should be interpreted with caution, because no study demonstrated low-risk of bias in all the assessed domains.
AB - Objective: The study compares low-level laser therapy with topical medications for treating aphthous ulcers.Methods: A search of articles in this systematic review was completed in six databases. Treatment and comparative groups comprised of patients subjected to laser therapy and topical medications, respectively. Two different treatment outcomes were considered; pain and size of the lesion. Risk of bias was assessed using the Revised Cochrane risk-of-bias tool for randomized trials.Results: From 109 articles, five randomized control trials fulfilled the selection criteria. The overall sample comprised of 98 males and 232 females, with a mean age of 32.4 years. The laser therapies in each included study had different active media and varying wavelengths. Topical medication used in the comparative group were triamcinolone acetonide, amlexanox, granofurin, and solcoseryl. Findings showed that patients who reported lower pain and decreased aphthous ulcer lesions were more in the laser therapy group than in the topical medication group.Conclusion: Low-level laser therapy was better in treating aphthous ulcer lesions in comparison to topical medications, and all laser wavelengths in the included reports were seen to be effective. However, the results should be interpreted with caution, because no study demonstrated low-risk of bias in all the assessed domains.
KW - aphthous ulcer
KW - recurrent aphthous stomatitis
KW - low-level laser therapy
KW - systematic review
KW - evidence-based practice
KW - DOUBLE-BLIND
KW - STOMATITIS
KW - EFFICACY
KW - PAIN
KW - OMEGA-3
U2 - 10.2147/JMDH.S281495
DO - 10.2147/JMDH.S281495
M3 - (Systematic) Review article
C2 - 33239881
SN - 1178-2390
VL - 13
SP - 1595
EP - 1605
JO - Journal of Multidisciplinary Healthcare
JF - Journal of Multidisciplinary Healthcare
ER -