Long-QT mutation p.K557E-Kv7.1: dominant-negative suppression of I-Ks, but preserved cAMP-dependent up-regulation

Roel Spätjens, Marketa Bebarova, Sandrine R. M. Seyen, Viola Lentink, Roselie J. Jongbloed, Yvonne H. J. M. Arens, Jordi Heijman, Paul G. A. Volders

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)216-225
JournalCardiovascular Research
Volume104
Issue number1
DOIs
Publication statusPublished - 1 Oct 2014

Keywords

  • Long-QT syndrome type 1
  • I-Ks
  • Potassium channel
  • Adrenergic regulation
  • KCNQ1

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