Local giant cell foreign body reaction after silicone injection for fecal incontinence in humans: two case reports.

B. van Wunnik*, A.L.C. Driessen, C. Baeten

*Corresponding author for this work

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

2 Citations (Web of Science)


Since the 1990s, one of the methods used for treating fecal incontinence due to internal anal sphincter defects has been the injection of bulking agents. The aim of this paper is to report two cases of local giant cell foreign body reaction after injection of PTQ(TM) in humans. To the best of the authors' knowledge, this is the first report of an adverse immune response to silicone injection in humans.
Original languageEnglish
Pages (from-to)395-397
JournalTechniques in coloproctology
Issue number5
Publication statusPublished - 1 Jan 2012

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