Abstract
BACKGROUND: Late gadolinium enhancement (LGE) is a widely used cardiac magnetic resonance imaging (MRI) technique to diagnose a broad range of ischemic and non-ischemic cardiomyopathies. Since its development and validation against histology already more than two decades ago, the clinical utility of LGE and its span of applications have increased considerably.
METHODS: In this review we will present the basic concepts of LGE imaging and its diagnostic and prognostic value, elaborate on recent developments and emerging methods, and finally discuss future prospects.
RESULTS: Continuous developments in 3 D imaging methods, motion correction techniques, water/fat-separated imaging, dark-blood methods, and scar quantification improved the performance and further expanded the clinical utility of LGE imaging.
CONCLUSION: LGE imaging is the current noninvasive reference standard for the assessment of myocardial viability. Improvements in spatial resolution, scar-to-blood contrast, and water/fat-separated imaging further strengthened its position.
KEY POINTS: · LGE MRI is the reference standard for the noninvasive assessment of myocardial viability. · LGE MRI is used to diagnose a broad range of non-ischemic cardiomyopathies in everyday clinical practice.. · Improvements in spatial resolution and scar-to-blood contrast further strengthened its position. · Continuous developments improve its performance and further expand its clinical utility.
CITATION FORMAT: · Holtackers RJ, Emrich T, Botnar RM et al. Late Gadolinium Enhancement Cardiac Magnetic Resonance Imaging: From Basic Concepts to Emerging Methods. Fortschr Röntgenstr 2022; DOI: 10.1055/a-1718-4355.
Original language | English |
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Pages (from-to) | 491-504 |
Number of pages | 14 |
Journal | RöFo-Fortschritte auf dem Gebiet der Röntgenstrahlen und der Bildgebenden Verfahren |
Volume | 194 |
Issue number | 05 |
Early online date | 23 Feb 2022 |
DOIs | |
Publication status | Published - May 2022 |
Keywords
- CONTRAST ENHANCEMENT
- DILATED CARDIOMYOPATHY
- EMISSION-COMPUTED-TOMOGRAPHY
- FIBROSIS
- HEART-DISEASE
- INVERSION-RECOVERY
- MICROVASCULAR OBSTRUCTION
- MR imaging
- MYOCARDIAL INFARCT SIZE
- PROGNOSTIC VALUE
- SCAR
- cardiac
- heart
- tissue characterization