TY - JOUR
T1 - Is Peripheral Artery Disease an Independent Predictor of Isolated Coronary Artery Bypass Outcome?
AU - Bonacchi, Massimo
AU - Parise, Orlando
AU - Matteucci, Francesco
AU - Tetta, Cecilia
AU - Moula, Amalia Ioanna
AU - Micali, Linda Renata
AU - Dokollari, Aleksander
AU - De Martino, Marco
AU - Sani, Guido
AU - Grasso, Andrea
AU - Prifti, Edvin
AU - Gelsomino, Sandro
N1 - Publisher Copyright:
© 2020 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ)
PY - 2020/10
Y1 - 2020/10
N2 - Aim The aim was to use a propensity score-based analysis to determine the impact of peripheral artery disease (PAD) on early outcomes after coronary artery bypass surgery grafting (CABG) in patients with PAD.Method We conducted a multicentre retrospective analysis of 11,311 consecutive patients who underwent CABG between 1997 and 2017. Patients with previous or concomitant vascular surgery were excluded. The main endpoints were death, stroke, and limb ischaemia requiring percutaneous or surgical revascularisation. Subgroup analyses were performed to test the interaction of PAD with concomitant factors.Results There was no difference in mortality in patients with and without PAD (p=0.06 and p=0.179, respectively). Patients with PAD had a greater incidence of stroke (p=0.04), acute kidney disease (p=0.003), and limb ischaemia requiring interventions (pConclusions The presence of PAD is associated, independently of other factors, with greater incidence of stroke, acute kidney disease, and limb ischaemia following CABG, irrespective of the technique employed. Operative mortality was greater in patients with PAD only when associated with long cardiopulmonary bypass and aortic cross-clamp times, and low cardiac output.
AB - Aim The aim was to use a propensity score-based analysis to determine the impact of peripheral artery disease (PAD) on early outcomes after coronary artery bypass surgery grafting (CABG) in patients with PAD.Method We conducted a multicentre retrospective analysis of 11,311 consecutive patients who underwent CABG between 1997 and 2017. Patients with previous or concomitant vascular surgery were excluded. The main endpoints were death, stroke, and limb ischaemia requiring percutaneous or surgical revascularisation. Subgroup analyses were performed to test the interaction of PAD with concomitant factors.Results There was no difference in mortality in patients with and without PAD (p=0.06 and p=0.179, respectively). Patients with PAD had a greater incidence of stroke (p=0.04), acute kidney disease (p=0.003), and limb ischaemia requiring interventions (pConclusions The presence of PAD is associated, independently of other factors, with greater incidence of stroke, acute kidney disease, and limb ischaemia following CABG, irrespective of the technique employed. Operative mortality was greater in patients with PAD only when associated with long cardiopulmonary bypass and aortic cross-clamp times, and low cardiac output.
KW - Coronary artery bypass
KW - Peripheral arterial disease
KW - Peripheral vascular disease
KW - LONG-TERM SURVIVAL
KW - VASCULAR-DISEASE
KW - PERIOPERATIVE STROKE
KW - REVASCULARIZATION
KW - SURGERY
KW - MORTALITY
KW - MANAGEMENT
KW - STENOSIS
KW - TIME
U2 - 10.1016/j.hlc.2020.01.013
DO - 10.1016/j.hlc.2020.01.013
M3 - Article
C2 - 32165084
SN - 1443-9506
VL - 29
SP - 1502
EP - 1510
JO - Heart Lung and Circulation
JF - Heart Lung and Circulation
IS - 10
ER -