Inferring transcription factor activity from microarray data reveals novel targets for toxicological investigations

T. M. Souza; T. van den Beucken; J. C. S. Kleinjans; D. G. J. Jennen

doi:10.1016/j.tox.2017.07.008

Inferring transcription factor activity from microarray data reveals novel targets for toxicological investigations

T. M. Souza^*, T. van den Beucken, J. C. S. Kleinjans, D. G. J. Jennen

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	101-107
Number of pages	7
Journal	Toxicology
Volume	389
DOIs	https://doi.org/10.1016/j.tox.2017.07.008
Publication status	Published - 15 Aug 2017

Keywords

Transcription factor
Microarray
Stress pathway
Carcinogenicity
Dili
PRIMARY HUMAN HEPATOCYTES
REGULATORY NETWORKS
RISK-ASSESSMENT
EXPRESSION
STRESS
LIVER
P53
HEPATOTOXICITY
RESPONSES
TOXICOGENOMICS

Access to Document

10.1016/j.tox.2017.07.008

Cite this

Souza, T. M., van den Beucken, T., Kleinjans, J. C. S., & Jennen, D. G. J. (2017). Inferring transcription factor activity from microarray data reveals novel targets for toxicological investigations. Toxicology, 389, 101-107. https://doi.org/10.1016/j.tox.2017.07.008

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keywords = "Transcription factor, Microarray, Stress pathway, Carcinogenicity, Dili, PRIMARY HUMAN HEPATOCYTES, REGULATORY NETWORKS, RISK-ASSESSMENT, EXPRESSION, STRESS, LIVER, P53, HEPATOTOXICITY, RESPONSES, TOXICOGENOMICS",

author = "Souza, {T. M.} and {van den Beucken}, T. and Kleinjans, {J. C. S.} and Jennen, {D. G. J.}",

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AU - Souza, T. M.

AU - van den Beucken, T.

AU - Kleinjans, J. C. S.

AU - Jennen, D. G. J.

PY - 2017/8/15

Y1 - 2017/8/15

KW - Transcription factor

KW - Microarray

KW - Stress pathway

KW - Carcinogenicity

KW - Dili

KW - PRIMARY HUMAN HEPATOCYTES

KW - REGULATORY NETWORKS

KW - RISK-ASSESSMENT

KW - EXPRESSION

KW - STRESS

KW - LIVER

KW - P53

KW - HEPATOTOXICITY

KW - RESPONSES

KW - TOXICOGENOMICS

U2 - 10.1016/j.tox.2017.07.008

DO - 10.1016/j.tox.2017.07.008

M3 - Article

VL - 389

SP - 101

EP - 107

JO - Toxicology

JF - Toxicology

SN - 0300-483X

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