Inferring transcription factor activity from microarray data reveals novel targets for toxicological investigations

T. M. Souza; T. van den Beucken; J. C. S. Kleinjans; D. G. J. Jennen

doi:10.1016/j.tox.2017.07.008

Inferring transcription factor activity from microarray data reveals novel targets for toxicological investigations

T. M. Souza^*, T. van den Beucken, J. C. S. Kleinjans, D. G. J. Jennen

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	101-107
Number of pages	7
Journal	Toxicology
Volume	389
DOIs	https://doi.org/10.1016/j.tox.2017.07.008
Publication status	Published - 15 Aug 2017

Keywords

Transcription factor
Microarray
Stress pathway
Carcinogenicity
Dili
PRIMARY HUMAN HEPATOCYTES
REGULATORY NETWORKS
RISK-ASSESSMENT
EXPRESSION
STRESS
LIVER
P53
HEPATOTOXICITY
RESPONSES
TOXICOGENOMICS

Access to Document

10.1016/j.tox.2017.07.008

Cite this

@article{b84fc7f6c70a4340b200d144c0a499ed,

title = "Inferring transcription factor activity from microarray data reveals novel targets for toxicological investigations",

keywords = "Transcription factor, Microarray, Stress pathway, Carcinogenicity, Dili, PRIMARY HUMAN HEPATOCYTES, REGULATORY NETWORKS, RISK-ASSESSMENT, EXPRESSION, STRESS, LIVER, P53, HEPATOTOXICITY, RESPONSES, TOXICOGENOMICS",

author = "Souza, {T. M.} and {van den Beucken}, T. and Kleinjans, {J. C. S.} and Jennen, {D. G. J.}",

year = "2017",

month = aug,

day = "15",

doi = "10.1016/j.tox.2017.07.008",

language = "English",

volume = "389",

pages = "101--107",

journal = "Toxicology",

issn = "0300-483X",

publisher = "Elsevier Ireland Ltd",

}

TY - JOUR

T1 - Inferring transcription factor activity from microarray data reveals novel targets for toxicological investigations

AU - Souza, T. M.

AU - van den Beucken, T.

AU - Kleinjans, J. C. S.

AU - Jennen, D. G. J.

PY - 2017/8/15

Y1 - 2017/8/15

KW - Transcription factor

KW - Microarray

KW - Stress pathway

KW - Carcinogenicity

KW - Dili

KW - PRIMARY HUMAN HEPATOCYTES

KW - REGULATORY NETWORKS

KW - RISK-ASSESSMENT

KW - EXPRESSION

KW - STRESS

KW - LIVER

KW - P53

KW - HEPATOTOXICITY

KW - RESPONSES

KW - TOXICOGENOMICS

U2 - 10.1016/j.tox.2017.07.008

DO - 10.1016/j.tox.2017.07.008

M3 - Article

C2 - 28743512

VL - 389

SP - 101

EP - 107

JO - Toxicology

JF - Toxicology

SN - 0300-483X

ER -