Inactivation of the E3 Ubiquitin Ligase IDOL Attenuates Diet-Induced Obesity and Metabolic Dysfunction in Mice

Nienke M. van Loon, Roelof Ottenhoff, Sander Kooijman, Martina Moeton, Saskia Scheij, Reinout L. P. Roscam Abbing, Marion J. J. Gijbels, Johannes H. M. Levels, Vincenzo Sorrentino, Jimmy F. P. Berbee, Patrick C. N. Rensen, Noam Zelcer

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1785-1795
Number of pages11
JournalArteriosclerosis Thrombosis and Vascular Biology
Volume38
Issue number8
DOIs
Publication statusPublished - 1 Aug 2018

Keywords

  • adipose tissue
  • brown
  • cholesterol
  • lipid metabolism
  • metabolic syndrome
  • obesity
  • ubiquitin-protein ligases
  • LOW-DENSITY-LIPOPROTEIN
  • FAMILY-MEMBERS VLDLR
  • ADIPOSE-TISSUE
  • INDUCIBLE DEGRADER
  • LDL RECEPTORS
  • CHOLESTEROL
  • PCSK9
  • DEGRADATION
  • PLASMA
  • GLUCOSE

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