Immunotoxicological consequences of perinatal chemical exposures

H. van Loveren; A. Piersma

doi:10.1016/j.toxlet.2003.12.028

Immunotoxicological consequences of perinatal chemical exposures

H. van Loveren^*, A. Piersma

^*Corresponding author for this work

NUTRIM School of Nutrition and Translational Research in Metabolism

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

The developing immune system may be especially vulnerable to the toxic effects of immunotoxicants. A number of chemicals has been identified that affect the developing immune system. Yet, so far there are no immune parameters included in current guidelines for developmental or reproductive toxicity testing. It is recommended that such guidelines are updated so that also the developing immune system is evaluated as a potential target of toxicity during developmental stages.

Original language	English
Pages (from-to)	141-145
Journal	Toxicology Letters
Volume	149
Issue number	1-3
DOIs	https://doi.org/10.1016/j.toxlet.2003.12.028
Publication status	Published - 1 Jan 2004

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10.1016/j.toxlet.2003.12.028

Cite this

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title = "Immunotoxicological consequences of perinatal chemical exposures",

abstract = "The developing immune system may be especially vulnerable to the toxic effects of immunotoxicants. A number of chemicals has been identified that affect the developing immune system. Yet, so far there are no immune parameters included in current guidelines for developmental or reproductive toxicity testing. It is recommended that such guidelines are updated so that also the developing immune system is evaluated as a potential target of toxicity during developmental stages.",

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AB - The developing immune system may be especially vulnerable to the toxic effects of immunotoxicants. A number of chemicals has been identified that affect the developing immune system. Yet, so far there are no immune parameters included in current guidelines for developmental or reproductive toxicity testing. It is recommended that such guidelines are updated so that also the developing immune system is evaluated as a potential target of toxicity during developmental stages.

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