Higher numbers of memory B-cells and Th2-cytokine skewing in high responders to hepatitis B vaccination

A. M. C. M. Doedee*, N. Kannegieter, K. Ozturk, H. van Loveren, R. Janssen, A. M. Buisman

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Web of Science)


In the present study, differences in hepatitis B surface antigen (HBsAg)-specific memory B-cell responses between low and high responders to hepatitis B vaccine (HepB), based on levels of antibodies against HBsAg (anti-HBs), were determined. In addition, HBsAg specific T-cell responses between high (anti-HBs level >20,000 IU/L) and low (anti-HBs level
Original languageEnglish
Pages (from-to)2281-2289
Issue number19
Publication statusPublished - 27 Apr 2016


  • Hepatitis B vaccination
  • Low and high responders
  • Anti-HBs levels
  • HBsAg-specific memory B-cells
  • HBsAg-specific memory T-cells
  • IL-13

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