High Rates of Antimicrobial Drug Resistance Gene Acquisition After International travel, the Netherlands

C.J.H. von Wintersdorff; J. Penders; E.E. Stobberingh; A.M.L. Oude Lashof; C.J.P.A. Hoebe; P.H.M. Savelkoul; P.F.G. Wolffs

doi:10.3201/eid2004.131718

High Rates of Antimicrobial Drug Resistance Gene Acquisition After International travel, the Netherlands

C.J.H. von Wintersdorff, J. Penders, E.E. Stobberingh, A.M.L. Oude Lashof, C.J.P.A. Hoebe, P.H.M. Savelkoul, P.F.G. Wolffs^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

We investigated the effect of international travel on the gut resistome of 122 healthy travelers from the Netherlands by using a targeted metagenomic approach. Our results confirm high acquisition rates of the extended-spectrum beta-lactamase encoding gene bla(CTX-M), documenting a rise in prevalence from 9.0% before travel to 33.6% after travel (p

Original language	English
Pages (from-to)	649-657
Number of pages	9
Journal	Emerging Infectious Diseases
Volume	20
Issue number	4
DOIs	https://doi.org/10.3201/eid2004.131718
Publication status	Published - Apr 2014

Keywords

MEDIATED QUINOLONE RESISTANCE
SPECTRUM BETA-LACTAMASES
ESCHERICHIA-COLI
FOREIGN TRAVEL
PLASMID
ENTEROBACTERIACEAE
PCR
COLONIZATION
DETERMINANTS
MICROBIOME

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10.3201/eid2004.131718Licence: CC BY

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Cite this

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title = "High Rates of Antimicrobial Drug Resistance Gene Acquisition After International travel, the Netherlands",

abstract = "We investigated the effect of international travel on the gut resistome of 122 healthy travelers from the Netherlands by using a targeted metagenomic approach. Our results confirm high acquisition rates of the extended-spectrum beta-lactamase encoding gene bla(CTX-M), documenting a rise in prevalence from 9.0% before travel to 33.6% after travel (p",

keywords = "MEDIATED QUINOLONE RESISTANCE, SPECTRUM BETA-LACTAMASES, ESCHERICHIA-COLI, FOREIGN TRAVEL, PLASMID, ENTEROBACTERIACEAE, PCR, COLONIZATION, DETERMINANTS, MICROBIOME",

author = "{von Wintersdorff}, C.J.H. and J. Penders and E.E. Stobberingh and {Oude Lashof}, A.M.L. and C.J.P.A. Hoebe and P.H.M. Savelkoul and P.F.G. Wolffs",

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AU - von Wintersdorff, C.J.H.

AU - Penders, J.

AU - Stobberingh, E.E.

AU - Oude Lashof, A.M.L.

AU - Hoebe, C.J.P.A.

AU - Savelkoul, P.H.M.

AU - Wolffs, P.F.G.

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AB - We investigated the effect of international travel on the gut resistome of 122 healthy travelers from the Netherlands by using a targeted metagenomic approach. Our results confirm high acquisition rates of the extended-spectrum beta-lactamase encoding gene bla(CTX-M), documenting a rise in prevalence from 9.0% before travel to 33.6% after travel (p

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KW - SPECTRUM BETA-LACTAMASES

KW - ESCHERICHIA-COLI

KW - FOREIGN TRAVEL

KW - PLASMID

KW - ENTEROBACTERIACEAE

KW - PCR

KW - COLONIZATION

KW - DETERMINANTS

KW - MICROBIOME

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