Hematopoietic Npc1 mutation shifts gut microbiota composition in Ldlr(-/-) mice on a high-fat, high-cholesterol diet

Tom Houben; John Penders; Yvonne Oligschlaeger; Ines A. Magro dos Reis; Marc-Jan Bonder; Debby P. Koonen; Jingyuan Fu; Marten H. Hofker; Ronit Shiri-Sverdlov

doi:10.1038/s41598-019-51525-x

Hematopoietic Npc1 mutation shifts gut microbiota composition in Ldlr(-/-) mice on a high-fat, high-cholesterol diet

Tom Houben, John Penders, Yvonne Oligschlaeger, Ines A. Magro dos Reis, Marc-Jan Bonder, Debby P. Koonen, Jingyuan Fu, Marten H. Hofker, Ronit Shiri-Sverdlov

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Article number	14956
Number of pages	11
Journal	Scientific Reports
Volume	9
DOIs	https://doi.org/10.1038/s41598-019-51525-x
Publication status	Published - 18 Oct 2019

Keywords

LOW-DENSITY-LIPOPROTEIN
INTESTINAL MICROBIOTA
INDUCED OBESITY
INFLAMMATION
RISK
GENE
ATHEROSCLEROSIS
HYPERCHOLESTEROLEMIA
ACCUMULATION
ENTEROTYPES

Access to Document

10.1038/s41598-019-51525-x

Cite this

Houben, T., Penders, J., Oligschlaeger, Y., dos Reis, I. A. M., Bonder, M-J., Koonen, D. P., Fu, J., Hofker, M. H., & Shiri-Sverdlov, R. (2019). Hematopoietic Npc1 mutation shifts gut microbiota composition in Ldlr(-/-) mice on a high-fat, high-cholesterol diet. Scientific Reports, 9, [14956]. https://doi.org/10.1038/s41598-019-51525-x

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title = "Hematopoietic Npc1 mutation shifts gut microbiota composition in Ldlr(-/-) mice on a high-fat, high-cholesterol diet",

keywords = "LOW-DENSITY-LIPOPROTEIN, INTESTINAL MICROBIOTA, INDUCED OBESITY, INFLAMMATION, RISK, GENE, ATHEROSCLEROSIS, HYPERCHOLESTEROLEMIA, ACCUMULATION, ENTEROTYPES",

author = "Tom Houben and John Penders and Yvonne Oligschlaeger and {dos Reis}, {Ines A. Magro} and Marc-Jan Bonder and Koonen, {Debby P.} and Jingyuan Fu and Hofker, {Marten H.} and Ronit Shiri-Sverdlov",

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doi = "10.1038/s41598-019-51525-x",

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Hematopoietic Npc1 mutation shifts gut microbiota composition in Ldlr(-/-) mice on a high-fat, high-cholesterol diet. / Houben, Tom ; Penders, John; Oligschlaeger, Yvonne; dos Reis, Ines A. Magro; Bonder, Marc-Jan; Koonen, Debby P.; Fu, Jingyuan; Hofker, Marten H.; Shiri-Sverdlov, Ronit.

In: Scientific Reports, Vol. 9, 14956, 18.10.2019.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Hematopoietic Npc1 mutation shifts gut microbiota composition in Ldlr(-/-) mice on a high-fat, high-cholesterol diet

AU - Houben, Tom

AU - Penders, John

AU - Oligschlaeger, Yvonne

AU - dos Reis, Ines A. Magro

AU - Bonder, Marc-Jan

AU - Koonen, Debby P.

AU - Fu, Jingyuan

AU - Hofker, Marten H.

AU - Shiri-Sverdlov, Ronit

PY - 2019/10/18

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KW - INTESTINAL MICROBIOTA

KW - INDUCED OBESITY

KW - INFLAMMATION

KW - RISK

KW - GENE

KW - ATHEROSCLEROSIS

KW - HYPERCHOLESTEROLEMIA

KW - ACCUMULATION

KW - ENTEROTYPES

U2 - 10.1038/s41598-019-51525-x

DO - 10.1038/s41598-019-51525-x

M3 - Article

VL - 9

JO - Scientific Reports

JF - Scientific Reports

SN - 2045-2322

M1 - 14956

ER -