Glutamate Signalling in Object Novelty Recognition Memory Tests

Elentina K. Argyrousi; Pim R. A. Heckman; Jos Prickaerts

doi:10.1016/B978-0-12-812012-5.00035-5

Glutamate Signalling in Object Novelty Recognition Memory Tests

Elentina K. Argyrousi^*, Pim R. A. Heckman^*, Jos Prickaerts^*

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic

Abstract

The object recognition and to a lesser extent the object location tests contributed to the better understanding of the role of glutamatergic signalling in memory. Pharmacological manipulation of glutamate signalling showed that its different components contribute to distinct stages of memory formation. Additionally positive modulation of glutamate transmission was shown to facilitate storage of object recognition memory, while its inhibition could be neuroprotective against excitotoxicity.

Original language	English
Title of host publication	Handbook of Object Novelty Recognition
Editors	Abdel Ennaceur, Maria Angelica de Souza Silva
Publisher	Elsevier
Pages	541-551
Number of pages	11
Volume	27
ISBN (Print)	978-0-12-812012-5
DOIs	https://doi.org/10.1016/B978-0-12-812012-5.00035-5
Publication status	Published - 2018

Keywords

Ionotropic glutamate receptors
Metabotropic glutamate receptors

Access to Document

10.1016/B978-0-12-812012-5.00035-5

Cite this

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