GEBR-7b, a novel PDE4D selective inhibitor that improves memory in rodents at non-emetic doses

O. Bruno, E. Fedele, J. Prickaerts, L. A. Parker, E. Canepa, Chiara Brullo, A. Cavallero, Elena Gardella, A. Balbi, C. Domenicotti, E. Bollen, Hieronymus J. M. Gijselaers, T. Vanmierlo, K. Erb, C. L. Limebeer, F. Argellati, U. M. Marinari, Maria Adelaide Pronzato, R. Ricciarelli

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)2054-2063
JournalBritish Journal of Pharmacology
Volume164
Issue number8
DOIs
Publication statusPublished - Dec 2011

Keywords

  • PDE4 inhibitor
  • memory
  • phosphodiesterase
  • cyclic AMP
  • rolipram
  • emesis

Cite this

Bruno, O. ; Fedele, E. ; Prickaerts, J. ; Parker, L. A. ; Canepa, E. ; Brullo, Chiara ; Cavallero, A. ; Gardella, Elena ; Balbi, A. ; Domenicotti, C. ; Bollen, E. ; Gijselaers, Hieronymus J. M. ; Vanmierlo, T. ; Erb, K. ; Limebeer, C. L. ; Argellati, F. ; Marinari, U. M. ; Pronzato, Maria Adelaide ; Ricciarelli, R. / GEBR-7b, a novel PDE4D selective inhibitor that improves memory in rodents at non-emetic doses. In: British Journal of Pharmacology. 2011 ; Vol. 164, No. 8. pp. 2054-2063.
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title = "GEBR-7b, a novel PDE4D selective inhibitor that improves memory in rodents at non-emetic doses",
keywords = "PDE4 inhibitor, memory, phosphodiesterase, cyclic AMP, rolipram, emesis",
author = "O. Bruno and E. Fedele and J. Prickaerts and Parker, {L. A.} and E. Canepa and Chiara Brullo and A. Cavallero and Elena Gardella and A. Balbi and C. Domenicotti and E. Bollen and Gijselaers, {Hieronymus J. M.} and T. Vanmierlo and K. Erb and Limebeer, {C. L.} and F. Argellati and Marinari, {U. M.} and Pronzato, {Maria Adelaide} and R. Ricciarelli",
year = "2011",
month = "12",
doi = "10.1111/j.1476-5381.2011.01524.x",
language = "English",
volume = "164",
pages = "2054--2063",
journal = "British Journal of Pharmacology",
issn = "0007-1188",
publisher = "Wiley",
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}

Bruno, O, Fedele, E, Prickaerts, J, Parker, LA, Canepa, E, Brullo, C, Cavallero, A, Gardella, E, Balbi, A, Domenicotti, C, Bollen, E, Gijselaers, HJM, Vanmierlo, T, Erb, K, Limebeer, CL, Argellati, F, Marinari, UM, Pronzato, MA & Ricciarelli, R 2011, 'GEBR-7b, a novel PDE4D selective inhibitor that improves memory in rodents at non-emetic doses', British Journal of Pharmacology, vol. 164, no. 8, pp. 2054-2063. https://doi.org/10.1111/j.1476-5381.2011.01524.x

GEBR-7b, a novel PDE4D selective inhibitor that improves memory in rodents at non-emetic doses. / Bruno, O.; Fedele, E.; Prickaerts, J.; Parker, L. A.; Canepa, E.; Brullo, Chiara; Cavallero, A.; Gardella, Elena; Balbi, A.; Domenicotti, C.; Bollen, E.; Gijselaers, Hieronymus J. M.; Vanmierlo, T.; Erb, K.; Limebeer, C. L.; Argellati, F.; Marinari, U. M.; Pronzato, Maria Adelaide; Ricciarelli, R.

In: British Journal of Pharmacology, Vol. 164, No. 8, 12.2011, p. 2054-2063.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - GEBR-7b, a novel PDE4D selective inhibitor that improves memory in rodents at non-emetic doses

AU - Bruno, O.

AU - Fedele, E.

AU - Prickaerts, J.

AU - Parker, L. A.

AU - Canepa, E.

AU - Brullo, Chiara

AU - Cavallero, A.

AU - Gardella, Elena

AU - Balbi, A.

AU - Domenicotti, C.

AU - Bollen, E.

AU - Gijselaers, Hieronymus J. M.

AU - Vanmierlo, T.

AU - Erb, K.

AU - Limebeer, C. L.

AU - Argellati, F.

AU - Marinari, U. M.

AU - Pronzato, Maria Adelaide

AU - Ricciarelli, R.

PY - 2011/12

Y1 - 2011/12

KW - PDE4 inhibitor

KW - memory

KW - phosphodiesterase

KW - cyclic AMP

KW - rolipram

KW - emesis

U2 - 10.1111/j.1476-5381.2011.01524.x

DO - 10.1111/j.1476-5381.2011.01524.x

M3 - Article

VL - 164

SP - 2054

EP - 2063

JO - British Journal of Pharmacology

JF - British Journal of Pharmacology

SN - 0007-1188

IS - 8

ER -