Gastrointestinal targets to modulate satiety and food intake

M.C.P. Geraedts

Research output: ThesisDoctoral ThesisInternal

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Diets that contain a relatively high level of proteins are regarded an effective treatment for weight control. Particularly for the prevention of weight increase after a period of weight loss. So far, it is not known whether it makes a difference which specific proteins are used in these diets. This dissertation studies which proteins have the greatest effect on a feeling of hunger and food intake. It turns out that proteins from peas have the greatest effect. It also turned out that inhibition of the decomposition of this protein in the stomach even increases the effect. Obese men ate less after they had been administered pea protein directly in the intestines, than after they had eaten this protein. These results can contribute to new perspectives in the treatment of overweight and obesity.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Maastricht University
  • Saris, Wim, Supervisor
  • Troost, Freddy, Supervisor
Award date3 Dec 2010
Place of PublicationMaastricht
Publication statusPublished - 1 Jan 2010


  • diets
  • proteins
  • feeling of hunger
  • food intake

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