Abstract
Purpose: Locally recurrent prostate cancer after previous radiation therapy remains challenging. One of the cura-tive options for these patients is salvage brachytherapy. There are no reports available on the use of a biodegradable rectal balloon implantation (RBI) in combination with brachytherapy in patients with recurrent prostate cancer after previous radiotherapy.Case presentation: Here, we report on a patient with a local recurrence at five years after previous low-dose-rate brachytherapy with a prescribed dose of 145 Gray (Gy) for a low-risk prostate adenocarcinoma. The patient experi-enced grade 3 rectal toxicity, which was resolved at the time of local recurrence. He was treated with focal high-dose-rate (HDR) brachytherapy of 2 fr. x 13 Gy after RBI implantation. Four years post-salvage treatment, there was no evidence of biochemical recurrence according Phoenix definition, and no gastro-intestinal or genitourinary toxicity.Conclusions: This case describes the use of RBI implantation in combination with a focal salvage HDR in a patient with recurrent disease, with significant initial grade 3 rectal toxicity after previous irradiation. The use of a biodegrad-able RBI proved to be a promising solution for such a patient; however, this method needs to be further investigated.
Original language | English |
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Pages (from-to) | 154-158 |
Number of pages | 5 |
Journal | Journal of Contemporary Brachytherapy |
Volume | 15 |
Issue number | 2 |
DOIs | |
Publication status | Published - 2023 |
Keywords
- prostate cancer
- brachytherapy
- salvage therapy
- rectal balloon implant
- DEFINITIVE RADIATION-THERAPY
- PRIMARY TUMOR
- FAILURE
- RADIOTHERAPY
- MEN
- TRICKS
- SITE
- MRI