TY - JOUR
T1 - Factors associated with Prolonged Inaction in the hypoglycaemic treatment in people with non-insulin dependent Type 2 Diabetes and elevated glycated haemoglobin
T2 - A registry-based cohort study
AU - Goderis, Geert
AU - Vaes, Bert
AU - Van den Akker, Marjan
AU - Elli, Steven
AU - Mathieu, Chantal
AU - Buntinx, Frank
AU - Henrard, Severine
PY - 2017/10
Y1 - 2017/10
N2 - Aims: To assess factors associated with Prolonged Inaction (PI) in insulin-naive patients with Type 2 Diabetes Mellitus (T2DM). PI was defined as the absence of treatment initiation or intensification for >= 12 months despite HbA1c >7% (53 mmol/mol).Methods: A retrospective cohort study was conducted based on data from Intego, a Flemish General Practice registry. The study period ranged from January 1, 2006 to December 31, 2013. Patients with insulin therapy before the start of the study period were excluded from the analysis. A mixed effects logistic regression was used to assess the association of PI with the presence of co-morbidities, co-medications, process parameters and bio-clinical parameters.Results: In a population of 2265 patients with T2DM, 578 insulin-naive patients presented with an HbA1c >7% (53 mmol/mol) for >= 12 months. Median follow-up was 1.2 years, median age 67 years, 55% were male. PI was present in 340 patients (59%) and associated with moderate to severe Chronic Kidney Disease, absence of a mental health disorder, less frequent HbA1c measurements, lower HbA1c values and a smaller number of co-medications.Conclusions: PI is highly prevalent in primary care, particularly in patients with less complex disease status and with less intensive follow-up. (C) 2017 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved.
AB - Aims: To assess factors associated with Prolonged Inaction (PI) in insulin-naive patients with Type 2 Diabetes Mellitus (T2DM). PI was defined as the absence of treatment initiation or intensification for >= 12 months despite HbA1c >7% (53 mmol/mol).Methods: A retrospective cohort study was conducted based on data from Intego, a Flemish General Practice registry. The study period ranged from January 1, 2006 to December 31, 2013. Patients with insulin therapy before the start of the study period were excluded from the analysis. A mixed effects logistic regression was used to assess the association of PI with the presence of co-morbidities, co-medications, process parameters and bio-clinical parameters.Results: In a population of 2265 patients with T2DM, 578 insulin-naive patients presented with an HbA1c >7% (53 mmol/mol) for >= 12 months. Median follow-up was 1.2 years, median age 67 years, 55% were male. PI was present in 340 patients (59%) and associated with moderate to severe Chronic Kidney Disease, absence of a mental health disorder, less frequent HbA1c measurements, lower HbA1c values and a smaller number of co-medications.Conclusions: PI is highly prevalent in primary care, particularly in patients with less complex disease status and with less intensive follow-up. (C) 2017 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved.
KW - Type 2 Diabetes Mellitus
KW - Clinical Inertia
KW - Oral anti-diabetic treatment
KW - Retrospective cohort study
KW - CLINICAL INERTIA
KW - GLYCEMIC CONTROL
KW - PRIMARY-CARE
KW - RETROSPECTIVE COHORT
KW - MANAGEMENT
U2 - 10.1016/j.pcd.2017.05.008
DO - 10.1016/j.pcd.2017.05.008
M3 - Article
SN - 1751-9918
VL - 11
SP - 482
EP - 489
JO - Primary Care Diabetes
JF - Primary Care Diabetes
IS - 5
ER -