Facial palsy and Valsalva-induced vertigo in a patient with temporal bone cystic fibrous dysplasia

Glen J. F. Kemps; Maud P. M. Tijssen; Raymond van de Berg; Jerome J. Waterval; Dirk H. P. M. Kunst

doi:10.1016/j.inat.2022.101622

Facial palsy and Valsalva-induced vertigo in a patient with temporal bone cystic fibrous dysplasia

Glen J. F. Kemps^*, Maud P. M. Tijssen, Raymond van de Berg, Jerome J. Waterval, Dirk H. P. M. Kunst

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

A 29-year-old woman, known with polyostotic fibrous dysplasia, presented with facial palsy, vertigo, and ipsi-lateral neck pain. Radiology revealed a large temporal bone cyst, extruding intracranially, eroding the labyrinth and Fallopian canal. Histopathology of the cyst wall retrieved through transmastoidal biopsy showed a mutation in the Gs-alpha gene, confirming cystic degeneration of fibrous dysplasia, making this a unique case in which both the inner ear and facial canal are affected by this condition.

Original language	English
Article number	101622
Number of pages	4
Journal	Interdisciplinary neurosurgery-Advanced techniques and case management
Volume	30
DOIs	https://doi.org/10.1016/j.inat.2022.101622
Publication status	Published - Dec 2022

Keywords

Fibrous dysplasia
Temporal bone
Facial palsy
Posterior semi -circular canal dehiscence

Access to Document

10.1016/j.inat.2022.101622Licence: CC BY

Cite this

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title = "Facial palsy and Valsalva-induced vertigo in a patient with temporal bone cystic fibrous dysplasia",

abstract = "A 29-year-old woman, known with polyostotic fibrous dysplasia, presented with facial palsy, vertigo, and ipsi-lateral neck pain. Radiology revealed a large temporal bone cyst, extruding intracranially, eroding the labyrinth and Fallopian canal. Histopathology of the cyst wall retrieved through transmastoidal biopsy showed a mutation in the Gs-alpha gene, confirming cystic degeneration of fibrous dysplasia, making this a unique case in which both the inner ear and facial canal are affected by this condition.",

keywords = "Fibrous dysplasia, Temporal bone, Facial palsy, Posterior semi -circular canal dehiscence",

author = "Kemps, {Glen J. F.} and Tijssen, {Maud P. M.} and {van de Berg}, Raymond and Waterval, {Jerome J.} and Kunst, {Dirk H. P. M.}",

year = "2022",

month = dec,

doi = "10.1016/j.inat.2022.101622",

language = "English",

volume = "30",

journal = "Interdisciplinary neurosurgery-Advanced techniques and case management",

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T1 - Facial palsy and Valsalva-induced vertigo in a patient with temporal bone cystic fibrous dysplasia

AU - Kemps, Glen J. F.

AU - Tijssen, Maud P. M.

AU - van de Berg, Raymond

AU - Waterval, Jerome J.

AU - Kunst, Dirk H. P. M.

PY - 2022/12

Y1 - 2022/12

N2 - A 29-year-old woman, known with polyostotic fibrous dysplasia, presented with facial palsy, vertigo, and ipsi-lateral neck pain. Radiology revealed a large temporal bone cyst, extruding intracranially, eroding the labyrinth and Fallopian canal. Histopathology of the cyst wall retrieved through transmastoidal biopsy showed a mutation in the Gs-alpha gene, confirming cystic degeneration of fibrous dysplasia, making this a unique case in which both the inner ear and facial canal are affected by this condition.

AB - A 29-year-old woman, known with polyostotic fibrous dysplasia, presented with facial palsy, vertigo, and ipsi-lateral neck pain. Radiology revealed a large temporal bone cyst, extruding intracranially, eroding the labyrinth and Fallopian canal. Histopathology of the cyst wall retrieved through transmastoidal biopsy showed a mutation in the Gs-alpha gene, confirming cystic degeneration of fibrous dysplasia, making this a unique case in which both the inner ear and facial canal are affected by this condition.

KW - Fibrous dysplasia

KW - Temporal bone

KW - Facial palsy

KW - Posterior semi -circular canal dehiscence

U2 - 10.1016/j.inat.2022.101622

DO - 10.1016/j.inat.2022.101622

M3 - Article

VL - 30

JO - Interdisciplinary neurosurgery-Advanced techniques and case management

JF - Interdisciplinary neurosurgery-Advanced techniques and case management

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ER -