Everyday cognitive failure in patients suffering from neurosarcoidosis

Mareye Voortman*, Jolanda De Vries, Celine M. R. Hendriks, Marjon D. P. Elfferich, Petal A. H. M. Wijnen, Marjolein Drent

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Web of Science)


Background: Cognitive failure is associated with memory and concentration problems. Previously, a prevalence of one third was found in a general sarcoidosis population. The aim of this study was to assess if neurosarcoidosis patients are at higher risk for developing everyday cognitive failure using the Cognitive Failure Questionnaire (CFQ) and to determine what factors were associated with cognitive failure. Methods: A cross-sectional web-based survey was conducted from April to May 2017 in a national sample of neurosarcoidosis patients. The survey asked about complaints and included 3 questionnaires (Fatigue Assessment Scale [FAS], Small Fiber Neuropathy Screening List [SFNSL] and CFQ. Data were compared to a general sarcoidosis population. Results: Of the 152 patients who completed the survey, 131 had neurosarcoidosis. The mean CFQ score was significantly higher in the neurosarcoidosis (45.6 +/- 20.7) compared to the general sarcoidosis population (36.2 +/- 15.9; p<0.0001). High CFQ scores (>= 43) were found in 55.7% and 33.9%, respectively (p

Original languageEnglish
Pages (from-to)2-10
Number of pages9
JournalSarcoidosis Vasculitis and Diffuse Lung Diseases
Issue number1
Publication statusPublished - 2019


  • neurosarcoidosis
  • cognitive failure
  • small fiber neuropathy (SFN)
  • fatigue
  • sarcoidosis

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