TY - JOUR
T1 - ERS/ESTS/ESTRO/ESR/ESTI/EFOMP statement on management of incidental findings from low dose CT screening for lung cancer
AU - O'Dowd, Emma L
AU - Tietzova, Ilona
AU - Bartlett, Emily
AU - Devaraj, Anand
AU - Biederer, Jürgen
AU - Brambilla, Marco
AU - Brunelli, Alessandro
AU - Chorostowska, Joanna
AU - Decaluwe, Herbert
AU - Deruysscher, Dirk
AU - De Wever, Walter
AU - Donoghue, Matthew
AU - Fabre, Aurelie
AU - Gaga, Mina
AU - van Geffen, Wouter
AU - Hardavella, Georgia
AU - Kauczor, Hans-Ulrich
AU - Kerpel-Fronius, Anna
AU - van Meerbeeck, Jan
AU - Nagavci, Blin
AU - Nestle, Ursula
AU - Novoa, Nuria
AU - Prosch, Helmut
AU - Prokop, Mathias
AU - Putora, Paul Martin
AU - Rawlinson, Janette
AU - Revel, Marie-Pierre
AU - Snoeckx, Annemiek
AU - Veronesi, Giulia
AU - Vliegenthart, Rozemarijn
AU - Weckbach, Sabine
AU - Blum, Torsten G
AU - Baldwin, David R
PY - 2023/10/6
Y1 - 2023/10/6
N2 - BACKGROUND: Screening for lung cancer with low radiation dose computed tomography has a strong evidence base, is being introduced in several European countries and is recommended as a new targeted cancer screening programme. The imperative now is to ensure that implementation follows an evidence-based process that will ensure clinical and cost effectiveness. This European Respiratory Society (ERS) task force was formed to provide an expert consensus for the management of incidental findings which can be adapted and followed during implementation. METHODS: A multi-European society collaborative group was convened. 23 topics were identified, primarily from an ERS statement on lung cancer screening, and a systematic review of the literature was conducted according to ERS standards. Initial review of abstracts was completed and full text was provided to members of the group for each topic. Sections were edited and the final document approved by all members and the ERS Science Council. RESULTS: Nine topics considered most important and frequent were reviewed as standalone topics (interstitial lung abnormalities, emphysema, bronchiectasis, consolidation, coronary calcification, aortic valve disease, mediastinal mass, mediastinal lymph nodes and thyroid abnormalities). Other topics considered of lower importance or infrequent were grouped into generic categories, suitable for general statements. CONCLUSIONS: This European collaborative group has produced an incidental findings statement that can be followed during lung cancer screening. It will ensure that an evidence-based approach is used for reporting and managing incidental findings, which will mean that harms are minimised and any programme is as cost-effective as possible.
AB - BACKGROUND: Screening for lung cancer with low radiation dose computed tomography has a strong evidence base, is being introduced in several European countries and is recommended as a new targeted cancer screening programme. The imperative now is to ensure that implementation follows an evidence-based process that will ensure clinical and cost effectiveness. This European Respiratory Society (ERS) task force was formed to provide an expert consensus for the management of incidental findings which can be adapted and followed during implementation. METHODS: A multi-European society collaborative group was convened. 23 topics were identified, primarily from an ERS statement on lung cancer screening, and a systematic review of the literature was conducted according to ERS standards. Initial review of abstracts was completed and full text was provided to members of the group for each topic. Sections were edited and the final document approved by all members and the ERS Science Council. RESULTS: Nine topics considered most important and frequent were reviewed as standalone topics (interstitial lung abnormalities, emphysema, bronchiectasis, consolidation, coronary calcification, aortic valve disease, mediastinal mass, mediastinal lymph nodes and thyroid abnormalities). Other topics considered of lower importance or infrequent were grouped into generic categories, suitable for general statements. CONCLUSIONS: This European collaborative group has produced an incidental findings statement that can be followed during lung cancer screening. It will ensure that an evidence-based approach is used for reporting and managing incidental findings, which will mean that harms are minimised and any programme is as cost-effective as possible.
U2 - 10.1183/13993003.00533-2023
DO - 10.1183/13993003.00533-2023
M3 - Article
SN - 0903-1936
VL - 62
JO - European Respiratory Journal
JF - European Respiratory Journal
IS - 4
M1 - 2300533
ER -