Epidemiological and histological findings implicate matrix Gla protein in diastolic left ventricular dysfunction

Fang-Fei Wei; Sander Trenson; Pierre Monney; Wen-Yi Yang; Menno Pruijm; Zhen-Yu Zhang; Yassine Bouatou; Qi-Fang Huang; Belen Ponte; Pierre-Yves Martin; Lutgarde Thijs; Tatiana Kuznetsova; Karel Allegaert; Stefan Janssens; Cees Vermeer; Peter Verhamme; Michel Burnier; Murielle Bochud; Georg Ehret; Jan A. Staessen

doi:10.1371/journal.pone.0193967

Epidemiological and histological findings implicate matrix Gla protein in diastolic left ventricular dysfunction

Fang-Fei Wei, Sander Trenson, Pierre Monney, Wen-Yi Yang, Menno Pruijm, Zhen-Yu Zhang, Yassine Bouatou, Qi-Fang Huang, Belen Ponte, Pierre-Yves Martin, Lutgarde Thijs, Tatiana Kuznetsova, Karel Allegaert, Stefan Janssens, Cees Vermeer, Peter Verhamme, Michel Burnier, Murielle Bochud, Georg Ehret, Jan A. Staessen

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Article number	e0193967
Number of pages	20
Journal	PLOS ONE
Volume	13
Issue number	3
DOIs	https://doi.org/10.1371/journal.pone.0193967
Publication status	Published - 12 Mar 2018

Keywords

BONE MORPHOGENETIC PROTEIN-4
PRESERVED EJECTION FRACTION
K-DEPENDENT PROTECTION
VITAMIN-K
HEART-FAILURE
MENAQUINONE-7 SUPPLEMENTATION
ARTERIAL STIFFNESS
POWERFUL PREDICTOR
GENERAL-POPULATION
FILLING PRESSURE
Multivariate Analysis
Humans
Middle Aged
Male
Ventricular Dysfunction, Left/diagnostic imaging
Myocardial Ischemia/diagnostic imaging
Young Adult
Netherlands
Extracellular Matrix Proteins/metabolism
Aged, 80 and over
Electrocardiography
Adult
Female
Heart Transplantation
Switzerland
Heart/diagnostic imaging
Calcium-Binding Proteins/metabolism
Myocardium/metabolism
Aged
Cardiomyopathy, Dilated/diagnostic imaging
Cohort Studies

Access to Document

10.1371/journal.pone.0193967

http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0193967&type=printable

Cite this

Wei, F-F., Trenson, S., Monney, P., Yang, W-Y., Pruijm, M., Zhang, Z-Y., Bouatou, Y., Huang, Q-F., Ponte, B., Martin, P-Y., Thijs, L., Kuznetsova, T., Allegaert, K., Janssens, S., Vermeer, C., Verhamme, P., Burnier, M., Bochud, M., Ehret, G., & Staessen, J. A. (2018). Epidemiological and histological findings implicate matrix Gla protein in diastolic left ventricular dysfunction. PLOS ONE, 13(3), [e0193967]. https://doi.org/10.1371/journal.pone.0193967

Wei, Fang-Fei ; Trenson, Sander ; Monney, Pierre ; Yang, Wen-Yi ; Pruijm, Menno ; Zhang, Zhen-Yu ; Bouatou, Yassine ; Huang, Qi-Fang ; Ponte, Belen ; Martin, Pierre-Yves ; Thijs, Lutgarde ; Kuznetsova, Tatiana ; Allegaert, Karel ; Janssens, Stefan ; Vermeer, Cees ; Verhamme, Peter ; Burnier, Michel ; Bochud, Murielle ; Ehret, Georg ; Staessen, Jan A. / Epidemiological and histological findings implicate matrix Gla protein in diastolic left ventricular dysfunction. In: PLOS ONE. 2018 ; Vol. 13, No. 3.

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title = "Epidemiological and histological findings implicate matrix Gla protein in diastolic left ventricular dysfunction",

keywords = "BONE MORPHOGENETIC PROTEIN-4, PRESERVED EJECTION FRACTION, K-DEPENDENT PROTECTION, VITAMIN-K, HEART-FAILURE, MENAQUINONE-7 SUPPLEMENTATION, ARTERIAL STIFFNESS, POWERFUL PREDICTOR, GENERAL-POPULATION, FILLING PRESSURE, Multivariate Analysis, Humans, Middle Aged, Male, Ventricular Dysfunction, Left/diagnostic imaging, Myocardial Ischemia/diagnostic imaging, Young Adult, Netherlands, Extracellular Matrix Proteins/metabolism, Aged, 80 and over, Electrocardiography, Adult, Female, Heart Transplantation, Switzerland, Heart/diagnostic imaging, Calcium-Binding Proteins/metabolism, Myocardium/metabolism, Aged, Cardiomyopathy, Dilated/diagnostic imaging, Cohort Studies",

author = "Fang-Fei Wei and Sander Trenson and Pierre Monney and Wen-Yi Yang and Menno Pruijm and Zhen-Yu Zhang and Yassine Bouatou and Qi-Fang Huang and Belen Ponte and Pierre-Yves Martin and Lutgarde Thijs and Tatiana Kuznetsova and Karel Allegaert and Stefan Janssens and Cees Vermeer and Peter Verhamme and Michel Burnier and Murielle Bochud and Georg Ehret and Staessen, {Jan A.}",

year = "2018",

month = mar,

day = "12",

doi = "10.1371/journal.pone.0193967",

language = "English",

volume = "13",

journal = "PLOS ONE",

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Wei, F-F, Trenson, S, Monney, P, Yang, W-Y, Pruijm, M, Zhang, Z-Y, Bouatou, Y, Huang, Q-F, Ponte, B, Martin, P-Y, Thijs, L, Kuznetsova, T, Allegaert, K, Janssens, S, Vermeer, C, Verhamme, P, Burnier, M, Bochud, M, Ehret, G & Staessen, JA 2018, 'Epidemiological and histological findings implicate matrix Gla protein in diastolic left ventricular dysfunction', PLOS ONE, vol. 13, no. 3, e0193967. https://doi.org/10.1371/journal.pone.0193967

Epidemiological and histological findings implicate matrix Gla protein in diastolic left ventricular dysfunction. / Wei, Fang-Fei; Trenson, Sander; Monney, Pierre; Yang, Wen-Yi; Pruijm, Menno; Zhang, Zhen-Yu; Bouatou, Yassine; Huang, Qi-Fang; Ponte, Belen; Martin, Pierre-Yves; Thijs, Lutgarde; Kuznetsova, Tatiana; Allegaert, Karel; Janssens, Stefan; Vermeer, Cees; Verhamme, Peter; Burnier, Michel; Bochud, Murielle; Ehret, Georg; Staessen, Jan A.

In: PLOS ONE, Vol. 13, No. 3, e0193967, 12.03.2018.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Epidemiological and histological findings implicate matrix Gla protein in diastolic left ventricular dysfunction

AU - Wei, Fang-Fei

AU - Trenson, Sander

AU - Monney, Pierre

AU - Yang, Wen-Yi

AU - Pruijm, Menno

AU - Zhang, Zhen-Yu

AU - Bouatou, Yassine

AU - Huang, Qi-Fang

AU - Ponte, Belen

AU - Martin, Pierre-Yves

AU - Thijs, Lutgarde

AU - Kuznetsova, Tatiana

AU - Allegaert, Karel

AU - Janssens, Stefan

AU - Vermeer, Cees

AU - Verhamme, Peter

AU - Burnier, Michel

AU - Bochud, Murielle

AU - Ehret, Georg

AU - Staessen, Jan A.

PY - 2018/3/12

Y1 - 2018/3/12

KW - BONE MORPHOGENETIC PROTEIN-4

KW - PRESERVED EJECTION FRACTION

KW - K-DEPENDENT PROTECTION

KW - VITAMIN-K

KW - HEART-FAILURE

KW - MENAQUINONE-7 SUPPLEMENTATION

KW - ARTERIAL STIFFNESS

KW - POWERFUL PREDICTOR

KW - GENERAL-POPULATION

KW - FILLING PRESSURE

KW - Multivariate Analysis

KW - Humans

KW - Middle Aged

KW - Male

KW - Ventricular Dysfunction, Left/diagnostic imaging

KW - Myocardial Ischemia/diagnostic imaging

KW - Young Adult

KW - Netherlands

KW - Extracellular Matrix Proteins/metabolism

KW - Aged, 80 and over

KW - Electrocardiography

KW - Adult

KW - Female

KW - Heart Transplantation

KW - Switzerland

KW - Heart/diagnostic imaging

KW - Calcium-Binding Proteins/metabolism

KW - Myocardium/metabolism

KW - Aged

KW - Cardiomyopathy, Dilated/diagnostic imaging

KW - Cohort Studies

U2 - 10.1371/journal.pone.0193967

DO - 10.1371/journal.pone.0193967

M3 - Article

VL - 13

JO - PLOS ONE

JF - PLOS ONE

SN - 1932-6203

IS - 3

M1 - e0193967

ER -