Enteroendocrine and tuft cells support Lgr5 stem cells on Paneth cell depletion

Johan H. van Es; Kay Wiebrands; Carmen Lopez-Iglesias; Marc van de Wetering; Laura Zeinstra; Maaike van den Born; Jeroen Korving; Nobuo Sasaki; Peter J. Peters; Alexander van Oudenaarden; Hans Clevers

doi:10.1073/pnas.1801888117

Enteroendocrine and tuft cells support Lgr5 stem cells on Paneth cell depletion

Johan H. van Es, Kay Wiebrands, Carmen Lopez-Iglesias, Marc van de Wetering, Laura Zeinstra, Maaike van den Born, Jeroen Korving, Nobuo Sasaki, Peter J. Peters, Alexander van Oudenaarden, Hans Clevers^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	26599-26605
Number of pages	7
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	116
Issue number	52
DOIs	https://doi.org/10.1073/pnas.1801888117
Publication status	Published - 26 Dec 2019

Keywords

intestine
Paneth cells
stem cells
Notch
SECRETORY PRECURSORS
SMALL-INTESTINE
COLON
ABLATION
MARKER
GENE

Access to Document

10.1073/pnas.1801888117

Cite this

van Es, J. H., Wiebrands, K., Lopez-Iglesias, C., de Wetering, M. V., Zeinstra, L., van den Born, M., Korving, J., Sasaki, N., Peters, P. J., van Oudenaarden, A., & Clevers, H. (2019). Enteroendocrine and tuft cells support Lgr5 stem cells on Paneth cell depletion. Proceedings of the National Academy of Sciences of the United States of America, 116(52), 26599-26605. https://doi.org/10.1073/pnas.1801888117

van Es, Johan H. ; Wiebrands, Kay ; Lopez-Iglesias, Carmen ; de Wetering, Marc van ; Zeinstra, Laura ; van den Born, Maaike ; Korving, Jeroen ; Sasaki, Nobuo ; Peters, Peter J. ; van Oudenaarden, Alexander ; Clevers, Hans. / Enteroendocrine and tuft cells support Lgr5 stem cells on Paneth cell depletion. In: Proceedings of the National Academy of Sciences of the United States of America. 2019 ; Vol. 116, No. 52. pp. 26599-26605.

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title = "Enteroendocrine and tuft cells support Lgr5 stem cells on Paneth cell depletion",

keywords = "intestine, Paneth cells, stem cells, Notch, SECRETORY PRECURSORS, SMALL-INTESTINE, COLON, ABLATION, MARKER, GENE",

author = "{van Es}, {Johan H.} and Kay Wiebrands and Carmen Lopez-Iglesias and {de Wetering}, {Marc van} and Laura Zeinstra and {van den Born}, Maaike and Jeroen Korving and Nobuo Sasaki and Peters, {Peter J.} and {van Oudenaarden}, Alexander and Hans Clevers",

year = "2019",

month = dec,

day = "26",

doi = "10.1073/pnas.1801888117",

language = "English",

volume = "116",

pages = "26599--26605",

journal = "Proceedings of the National Academy of Sciences of the United States of America",

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publisher = "National Academy of Sciences",

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van Es, JH, Wiebrands, K, Lopez-Iglesias, C, de Wetering, MV, Zeinstra, L, van den Born, M, Korving, J, Sasaki, N, Peters, PJ, van Oudenaarden, A & Clevers, H 2019, 'Enteroendocrine and tuft cells support Lgr5 stem cells on Paneth cell depletion', Proceedings of the National Academy of Sciences of the United States of America, vol. 116, no. 52, pp. 26599-26605. https://doi.org/10.1073/pnas.1801888117

Enteroendocrine and tuft cells support Lgr5 stem cells on Paneth cell depletion. / van Es, Johan H.; Wiebrands, Kay; Lopez-Iglesias, Carmen; de Wetering, Marc van; Zeinstra, Laura; van den Born, Maaike; Korving, Jeroen; Sasaki, Nobuo; Peters, Peter J.; van Oudenaarden, Alexander; Clevers, Hans.

In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, No. 52, 26.12.2019, p. 26599-26605.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Enteroendocrine and tuft cells support Lgr5 stem cells on Paneth cell depletion

AU - van Es, Johan H.

AU - Wiebrands, Kay

AU - Lopez-Iglesias, Carmen

AU - de Wetering, Marc van

AU - Zeinstra, Laura

AU - van den Born, Maaike

AU - Korving, Jeroen

AU - Sasaki, Nobuo

AU - Peters, Peter J.

AU - van Oudenaarden, Alexander

AU - Clevers, Hans

PY - 2019/12/26

Y1 - 2019/12/26

KW - intestine

KW - Paneth cells

KW - stem cells

KW - Notch

KW - SECRETORY PRECURSORS

KW - SMALL-INTESTINE

KW - COLON

KW - ABLATION

KW - MARKER

KW - GENE

U2 - 10.1073/pnas.1801888117

DO - 10.1073/pnas.1801888117

M3 - Article

C2 - 31843916

VL - 116

SP - 26599

EP - 26605

JO - Proceedings of the National Academy of Sciences of the United States of America

JF - Proceedings of the National Academy of Sciences of the United States of America

SN - 0027-8424

IS - 52

ER -