Effect of an Internet-based, personalized nutrition randomized trial on dietary changes associated with the Mediterranean diet: the Food4Me Study

Katherine M. Livingstone, Carlos Celis-Morales, Santiago Navas-Carretero, Rodrigo San-Cristobal, Anna L. Macready, Rosalind Fallaize, Hannah Forster, Clara Woolhead, Clare B. O'Donovan, Cyril F. M. Marsaux, Silvia Kolossa, Lydia Tsirigoti, Christina P. Lambrinou, George Moschonis, Magdalena Godlewska, Agnieszka Surwillo, Christian A. Drevon, Yannis Manios, Iwona Traczyk, Eileen R. GibneyLorraine Brennan, Marianne C. Walsh, Julie A. Lovegrove, Wim H. Saris, Hannelore Daniel, Mike Gibney, J. Alfredo Martinez, John C. Mathers*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Background: Little is known about the efficacy of personalized nutrition (PN) interventions for improving consumption of a Mediterranean diet (MedDiet). Objective: The objective was to evaluate the effect of a PN intervention on dietary changes associated with the MedDiet. Design: Participants (n = 1607) were recruited into a 6-mo, Internet-based, PN randomized controlled trial (Food4Me) designed to evaluate the effect of PN on dietary change. Participants were randomly assigned to receive conventional dietary advice [control; level 0 (L0)] or PN advice on the basis of current diet [level 1 (L1)], diet and phenotype [level 2 (L2)], or diet, phenotype, and genotype [level 3 (L3)]. Dietary intakes from food-frequency questionnaires at baseline and at 6 mo were converted to a MedDiet score. Linear regression compared participant characteristics between high (>5) and low (
Original languageEnglish
Pages (from-to)288-297
JournalAmerican Journal of Clinical Nutrition
Issue number2
Publication statusPublished - 1 Aug 2016


  • Mediterranean diet
  • Food4Me
  • personalized nutrition
  • Internet-based
  • European adults

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