Ectopic lipid deposition in muscle and liver, quantified by proton magnetic resonance spectroscopy

Mijke Buitinga; Pandichelvam Veeraiah; Florian Haans; Vera B Schrauwen-Hinderling

doi:10.1002/oby.23865

Ectopic lipid deposition in muscle and liver, quantified by proton magnetic resonance spectroscopy

Mijke Buitinga, Pandichelvam Veeraiah, Florian Haans, Vera B Schrauwen-Hinderling^*

^*Corresponding author for this work

Research output: Contribution to journal › (Systematic) Review article › peer-review

Abstract

Advances in the development of noninvasive imaging techniques have spurred investigations into ectopic lipid deposition in the liver and muscle and its implications in the development of metabolic diseases such as type 2 diabetes. Computed tomography and ultrasound have been applied in the past, though magnetic resonance-based methods are currently considered the gold standard as they allow more accurate quantitative detection of ectopic lipid stores. This review focuses on methodological considerations of magnetic resonance-based methods to image hepatic and muscle fat fractions, and it emphasizes anatomical and morphological aspects and how these may influence data acquisition, analysis, and interpretation.

Original language	English
Pages (from-to)	2447-2459
Number of pages	12
Journal	Obesity
Volume	31
Issue number	10
Early online date	5 Sept 2023
DOIs	https://doi.org/10.1002/oby.23865
Publication status	Published - Oct 2023

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10.1002/oby.23865Licence: CC BY-NC-ND

Cite this

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title = "Ectopic lipid deposition in muscle and liver, quantified by proton magnetic resonance spectroscopy",

abstract = "Advances in the development of noninvasive imaging techniques have spurred investigations into ectopic lipid deposition in the liver and muscle and its implications in the development of metabolic diseases such as type 2 diabetes. Computed tomography and ultrasound have been applied in the past, though magnetic resonance-based methods are currently considered the gold standard as they allow more accurate quantitative detection of ectopic lipid stores. This review focuses on methodological considerations of magnetic resonance-based methods to image hepatic and muscle fat fractions, and it emphasizes anatomical and morphological aspects and how these may influence data acquisition, analysis, and interpretation.",

author = "Mijke Buitinga and Pandichelvam Veeraiah and Florian Haans and Schrauwen-Hinderling, {Vera B}",

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AU - Buitinga, Mijke

AU - Veeraiah, Pandichelvam

AU - Haans, Florian

AU - Schrauwen-Hinderling, Vera B

PY - 2023/10

Y1 - 2023/10

N2 - Advances in the development of noninvasive imaging techniques have spurred investigations into ectopic lipid deposition in the liver and muscle and its implications in the development of metabolic diseases such as type 2 diabetes. Computed tomography and ultrasound have been applied in the past, though magnetic resonance-based methods are currently considered the gold standard as they allow more accurate quantitative detection of ectopic lipid stores. This review focuses on methodological considerations of magnetic resonance-based methods to image hepatic and muscle fat fractions, and it emphasizes anatomical and morphological aspects and how these may influence data acquisition, analysis, and interpretation.

AB - Advances in the development of noninvasive imaging techniques have spurred investigations into ectopic lipid deposition in the liver and muscle and its implications in the development of metabolic diseases such as type 2 diabetes. Computed tomography and ultrasound have been applied in the past, though magnetic resonance-based methods are currently considered the gold standard as they allow more accurate quantitative detection of ectopic lipid stores. This review focuses on methodological considerations of magnetic resonance-based methods to image hepatic and muscle fat fractions, and it emphasizes anatomical and morphological aspects and how these may influence data acquisition, analysis, and interpretation.

U2 - 10.1002/oby.23865

DO - 10.1002/oby.23865

M3 - (Systematic) Review article

SN - 1930-7381

VL - 31

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