Early prediction of thiopurine-induced hepatotoxicity in inflammatory bowel disease

D. R. Wong; M. J. H. Coenen; L. J. J. Derijks; S. H. Vermeulen; C. J. van  Marrewijk; O. H. Klungel; H. Scheffer; B. Franke; H. -J. Guchelaar; D. J. de  Jong; L. G. J. B. Engels; A. L. M. Verbeek; TOPIC Recruitment Team; Ad Masclee; P. M. Hooymans

doi:10.1111/apt.13879

Early prediction of thiopurine-induced hepatotoxicity in inflammatory bowel disease

D. R. Wong^*, M. J. H. Coenen, L. J. J. Derijks, S. H. Vermeulen, C. J. van Marrewijk, O. H. Klungel, H. Scheffer, B. Franke, H. -J. Guchelaar, D. J. de Jong, L. G. J. B. Engels, A. L. M. Verbeek, TOPIC Recruitment Team, Ad Masclee, P. M. Hooymans

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	391-402
Number of pages	12
Journal	Alimentary Pharmacology & Therapeutics
Volume	45
Issue number	3
DOIs	https://doi.org/10.1111/apt.13879
Publication status	Published - Feb 2017

Keywords

INDUCED LIVER-INJURY
S-METHYLTRANSFERASE ACTIVITY
AZATHIOPRINE
THERAPY
PHARMACOGENETICS
6-MERCAPTOPURINE
MERCAPTOPURINE
6-THIOGUANINE
PHARMACOKINETICS
ALLOPURINOL

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10.1111/apt.13879

Cite this

Wong, D. R., Coenen, M. J. H., Derijks, L. J. J., Vermeulen, S. H., van Marrewijk, C. J., Klungel, O. H., Scheffer, H., Franke, B., Guchelaar, H. -J., de Jong, D. J., Engels, L. G. J. B., Verbeek, A. L. M., TOPIC Recruitment Team, Masclee, A., & Hooymans, P. M. (2017). Early prediction of thiopurine-induced hepatotoxicity in inflammatory bowel disease. Alimentary Pharmacology & Therapeutics, 45(3), 391-402. https://doi.org/10.1111/apt.13879

Wong, D. R. ; Coenen, M. J. H. ; Derijks, L. J. J. ; Vermeulen, S. H. ; van Marrewijk, C. J. ; Klungel, O. H. ; Scheffer, H. ; Franke, B. ; Guchelaar, H. -J. ; de Jong, D. J. ; Engels, L. G. J. B. ; Verbeek, A. L. M. ; TOPIC Recruitment Team ; Masclee, Ad ; Hooymans, P. M. / Early prediction of thiopurine-induced hepatotoxicity in inflammatory bowel disease. In: Alimentary Pharmacology & Therapeutics. 2017 ; Vol. 45, No. 3. pp. 391-402.

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title = "Early prediction of thiopurine-induced hepatotoxicity in inflammatory bowel disease",

keywords = "INDUCED LIVER-INJURY, S-METHYLTRANSFERASE ACTIVITY, AZATHIOPRINE, THERAPY, PHARMACOGENETICS, 6-MERCAPTOPURINE, MERCAPTOPURINE, 6-THIOGUANINE, PHARMACOKINETICS, ALLOPURINOL",

author = "Wong, {D. R.} and Coenen, {M. J. H.} and Derijks, {L. J. J.} and Vermeulen, {S. H.} and {van Marrewijk}, {C. J.} and Klungel, {O. H.} and H. Scheffer and B. Franke and Guchelaar, {H. -J.} and {de Jong}, {D. J.} and Engels, {L. G. J. B.} and Verbeek, {A. L. M.} and {TOPIC Recruitment Team} and Ad Masclee and Hooymans, {P. M.}",

year = "2017",

month = feb,

doi = "10.1111/apt.13879",

language = "English",

volume = "45",

pages = "391--402",

journal = "Alimentary Pharmacology & Therapeutics",

issn = "0269-2813",

publisher = "Wiley",

number = "3",

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Wong, DR, Coenen, MJH, Derijks, LJJ, Vermeulen, SH, van Marrewijk, CJ, Klungel, OH, Scheffer, H, Franke, B, Guchelaar, H-J, de Jong, DJ, Engels, LGJB, Verbeek, ALM, TOPIC Recruitment Team, Masclee, A & Hooymans, PM 2017, 'Early prediction of thiopurine-induced hepatotoxicity in inflammatory bowel disease', Alimentary Pharmacology & Therapeutics, vol. 45, no. 3, pp. 391-402. https://doi.org/10.1111/apt.13879

Early prediction of thiopurine-induced hepatotoxicity in inflammatory bowel disease. / Wong, D. R.; Coenen, M. J. H.; Derijks, L. J. J.; Vermeulen, S. H.; van Marrewijk, C. J.; Klungel, O. H.; Scheffer, H.; Franke, B.; Guchelaar, H. -J.; de Jong, D. J.; Engels, L. G. J. B.; Verbeek, A. L. M.; TOPIC Recruitment Team ; Masclee, Ad; Hooymans, P. M.

In: Alimentary Pharmacology & Therapeutics, Vol. 45, No. 3, 02.2017, p. 391-402.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Early prediction of thiopurine-induced hepatotoxicity in inflammatory bowel disease

AU - Wong, D. R.

AU - Coenen, M. J. H.

AU - Derijks, L. J. J.

AU - Vermeulen, S. H.

AU - van Marrewijk, C. J.

AU - Klungel, O. H.

AU - Scheffer, H.

AU - Franke, B.

AU - Guchelaar, H. -J.

AU - de Jong, D. J.

AU - Engels, L. G. J. B.

AU - Verbeek, A. L. M.

AU - TOPIC Recruitment Team

AU - Masclee, Ad

AU - Hooymans, P. M.

PY - 2017/2

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KW - S-METHYLTRANSFERASE ACTIVITY

KW - AZATHIOPRINE

KW - THERAPY

KW - PHARMACOGENETICS

KW - 6-MERCAPTOPURINE

KW - MERCAPTOPURINE

KW - 6-THIOGUANINE

KW - PHARMACOKINETICS

KW - ALLOPURINOL

U2 - 10.1111/apt.13879

DO - 10.1111/apt.13879

M3 - Article

C2 - 27943397

VL - 45

SP - 391

EP - 402

JO - Alimentary Pharmacology & Therapeutics

JF - Alimentary Pharmacology & Therapeutics

SN - 0269-2813

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ER -