Abstract

Background: Survivors of a cardiac arrest frequently have cognitive and emotional problems and their quality of life is at risk. We developed a brief nursing intervention to detect cognitive and emotional problems, provide information and support, promote self-management, and refer them to specialised care if necessary. This study examined its effectiveness.

Methods: Multicentre randomised controlled trial with measurements at two weeks, three months and twelve months after cardiac arrest. 185 adult cardiac arrest survivors and 155 caregivers participated. Primary outcome measures were societal participation and quality of life of the survivors at one year. Secondary outcomes were the patient's cognitive functioning, emotional state, extended daily activities and return to work, and the caregiver's well-being. Data were analysed using 'intention to treat' linear mixed model analyses.

Results: After one year, patients in the intervention group had a significantly better quality of life on SF-36 domains Role Emotional (estimated mean differences (EMD) = 16.38, p = 0.006), Mental Health (EMD = 6.87, p = 0.003) and General Health (EMD = 8.07, p = 0.010), but there was no significant difference with regard to societal participation. On the secondary outcome measures, survivors scored significantly better on overall emotional state (HADS total, EMD = -3.25, p = 0.002) and anxiety (HADS anxiety, EMD = -1.79, p = 0.001) at one year. Furthermore, at three months more people were back at work (50% versus 21%, p = 0.006). No significant differences were found for caregiver outcomes.

Conclusion: The outcomes of cardiac arrest survivors can be improved by an intervention focused on detecting and managing the cognitive and emotional consequences of a cardiac arrest. Trial registration: Current controlled trials, ISRCTN74835019. (C) 2015 Elsevier Ireland Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)8-16
Number of pages9
JournalInternational Journal of Cardiology
Volume193
DOIs
Publication statusPublished - 15 Aug 2015

Keywords

  • Cardiac arrest
  • Resuscitation
  • Cognitive impairments
  • Psychosocial intervention
  • Rehabilitation
  • Quality of life
  • PROGNOSTIC ASSOCIATION
  • MYOCARDIAL-INFARCTION
  • MULTIPLE-SCLEROSIS
  • BRAIN-INJURY
  • STAND STILL
  • EVENT SCALE
  • VALIDATION
  • SURVIVORS
  • RELIABILITY
  • REHABILITATION

Cite this

@article{91d3c9d5ae544c61b6b323f74de19ee1,
title = "Early neurologically-focused follow-up after cardiac arrest improves quality of life at one year: A randomised controlled trial",
abstract = "Background: Survivors of a cardiac arrest frequently have cognitive and emotional problems and their quality of life is at risk. We developed a brief nursing intervention to detect cognitive and emotional problems, provide information and support, promote self-management, and refer them to specialised care if necessary. This study examined its effectiveness.Methods: Multicentre randomised controlled trial with measurements at two weeks, three months and twelve months after cardiac arrest. 185 adult cardiac arrest survivors and 155 caregivers participated. Primary outcome measures were societal participation and quality of life of the survivors at one year. Secondary outcomes were the patient's cognitive functioning, emotional state, extended daily activities and return to work, and the caregiver's well-being. Data were analysed using 'intention to treat' linear mixed model analyses.Results: After one year, patients in the intervention group had a significantly better quality of life on SF-36 domains Role Emotional (estimated mean differences (EMD) = 16.38, p = 0.006), Mental Health (EMD = 6.87, p = 0.003) and General Health (EMD = 8.07, p = 0.010), but there was no significant difference with regard to societal participation. On the secondary outcome measures, survivors scored significantly better on overall emotional state (HADS total, EMD = -3.25, p = 0.002) and anxiety (HADS anxiety, EMD = -1.79, p = 0.001) at one year. Furthermore, at three months more people were back at work (50{\%} versus 21{\%}, p = 0.006). No significant differences were found for caregiver outcomes.Conclusion: The outcomes of cardiac arrest survivors can be improved by an intervention focused on detecting and managing the cognitive and emotional consequences of a cardiac arrest. Trial registration: Current controlled trials, ISRCTN74835019. (C) 2015 Elsevier Ireland Ltd. All rights reserved.",
keywords = "Cardiac arrest, Resuscitation, Cognitive impairments, Psychosocial intervention, Rehabilitation, Quality of life, PROGNOSTIC ASSOCIATION, MYOCARDIAL-INFARCTION, MULTIPLE-SCLEROSIS, BRAIN-INJURY, STAND STILL, EVENT SCALE, VALIDATION, SURVIVORS, RELIABILITY, REHABILITATION",
author = "V.R.M. Moulaert and {van Heugten}, C.M. and B. Winkens and W.G.M. Bakx and {de Krom}, M.C.F.T.M. and T.P.M. Gorgels and D.T. Wade and J.A. Verbunt",
year = "2015",
month = "8",
day = "15",
doi = "10.1016/j.ijcard.2015.04.229",
language = "English",
volume = "193",
pages = "8--16",
journal = "International Journal of Cardiology",
issn = "0167-5273",
publisher = "Elsevier Ireland Ltd",

}

Early neurologically-focused follow-up after cardiac arrest improves quality of life at one year: A randomised controlled trial. / Moulaert, V.R.M.; van Heugten, C.M.; Winkens, B.; Bakx, W.G.M.; de Krom, M.C.F.T.M.; Gorgels, T.P.M.; Wade, D.T.; Verbunt, J.A.

In: International Journal of Cardiology, Vol. 193, 15.08.2015, p. 8-16.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Early neurologically-focused follow-up after cardiac arrest improves quality of life at one year: A randomised controlled trial

AU - Moulaert, V.R.M.

AU - van Heugten, C.M.

AU - Winkens, B.

AU - Bakx, W.G.M.

AU - de Krom, M.C.F.T.M.

AU - Gorgels, T.P.M.

AU - Wade, D.T.

AU - Verbunt, J.A.

PY - 2015/8/15

Y1 - 2015/8/15

N2 - Background: Survivors of a cardiac arrest frequently have cognitive and emotional problems and their quality of life is at risk. We developed a brief nursing intervention to detect cognitive and emotional problems, provide information and support, promote self-management, and refer them to specialised care if necessary. This study examined its effectiveness.Methods: Multicentre randomised controlled trial with measurements at two weeks, three months and twelve months after cardiac arrest. 185 adult cardiac arrest survivors and 155 caregivers participated. Primary outcome measures were societal participation and quality of life of the survivors at one year. Secondary outcomes were the patient's cognitive functioning, emotional state, extended daily activities and return to work, and the caregiver's well-being. Data were analysed using 'intention to treat' linear mixed model analyses.Results: After one year, patients in the intervention group had a significantly better quality of life on SF-36 domains Role Emotional (estimated mean differences (EMD) = 16.38, p = 0.006), Mental Health (EMD = 6.87, p = 0.003) and General Health (EMD = 8.07, p = 0.010), but there was no significant difference with regard to societal participation. On the secondary outcome measures, survivors scored significantly better on overall emotional state (HADS total, EMD = -3.25, p = 0.002) and anxiety (HADS anxiety, EMD = -1.79, p = 0.001) at one year. Furthermore, at three months more people were back at work (50% versus 21%, p = 0.006). No significant differences were found for caregiver outcomes.Conclusion: The outcomes of cardiac arrest survivors can be improved by an intervention focused on detecting and managing the cognitive and emotional consequences of a cardiac arrest. Trial registration: Current controlled trials, ISRCTN74835019. (C) 2015 Elsevier Ireland Ltd. All rights reserved.

AB - Background: Survivors of a cardiac arrest frequently have cognitive and emotional problems and their quality of life is at risk. We developed a brief nursing intervention to detect cognitive and emotional problems, provide information and support, promote self-management, and refer them to specialised care if necessary. This study examined its effectiveness.Methods: Multicentre randomised controlled trial with measurements at two weeks, three months and twelve months after cardiac arrest. 185 adult cardiac arrest survivors and 155 caregivers participated. Primary outcome measures were societal participation and quality of life of the survivors at one year. Secondary outcomes were the patient's cognitive functioning, emotional state, extended daily activities and return to work, and the caregiver's well-being. Data were analysed using 'intention to treat' linear mixed model analyses.Results: After one year, patients in the intervention group had a significantly better quality of life on SF-36 domains Role Emotional (estimated mean differences (EMD) = 16.38, p = 0.006), Mental Health (EMD = 6.87, p = 0.003) and General Health (EMD = 8.07, p = 0.010), but there was no significant difference with regard to societal participation. On the secondary outcome measures, survivors scored significantly better on overall emotional state (HADS total, EMD = -3.25, p = 0.002) and anxiety (HADS anxiety, EMD = -1.79, p = 0.001) at one year. Furthermore, at three months more people were back at work (50% versus 21%, p = 0.006). No significant differences were found for caregiver outcomes.Conclusion: The outcomes of cardiac arrest survivors can be improved by an intervention focused on detecting and managing the cognitive and emotional consequences of a cardiac arrest. Trial registration: Current controlled trials, ISRCTN74835019. (C) 2015 Elsevier Ireland Ltd. All rights reserved.

KW - Cardiac arrest

KW - Resuscitation

KW - Cognitive impairments

KW - Psychosocial intervention

KW - Rehabilitation

KW - Quality of life

KW - PROGNOSTIC ASSOCIATION

KW - MYOCARDIAL-INFARCTION

KW - MULTIPLE-SCLEROSIS

KW - BRAIN-INJURY

KW - STAND STILL

KW - EVENT SCALE

KW - VALIDATION

KW - SURVIVORS

KW - RELIABILITY

KW - REHABILITATION

U2 - 10.1016/j.ijcard.2015.04.229

DO - 10.1016/j.ijcard.2015.04.229

M3 - Article

VL - 193

SP - 8

EP - 16

JO - International Journal of Cardiology

JF - International Journal of Cardiology

SN - 0167-5273

ER -