Dose requirements for idarucizumab reversal of dabigatran in a lethal porcine trauma model with continuous bleeding

Markus Honickel, Henri M. Spronk, Rolf Rossaint, Christian Stoppe, Joanne van Ryn, Hugo ten Cate, Oliver Grottke*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1370-1378
Number of pages9
JournalThrombosis and Haemostasis
Volume117
Issue number7
DOIs
Publication statusPublished - Jul 2017

Keywords

  • Anticoagulants
  • antidote
  • dabigatran
  • idarucizumab
  • trauma
  • PROTHROMBIN COMPLEX CONCENTRATE
  • ORAL ANTICOAGULANTS
  • BLOOD-LOSS
  • EX-VIVO
  • ANTIDOTE
  • PHARMACOKINETICS
  • TOLERABILITY
  • VOLUNTEERS
  • EFFICACY
  • SAFETY

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