Does proteolysis explain glutamine release from the septic brain?

C.H. Dejong*, S.W. Olde Damink

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


ABSTRACT: Berg and colleagues report on amino acid exchange across the human brain during endotoxin infusion. Lipopolysaccharide infusion induced a decrease in the ratio between branched chain amino acids and aromatic amino acids, increased unidirectional phenylalanine uptake, and increased net brain glutamine release. Cerebral proteolysis is suggested to play a role, but the question is whether this is the case and why this would happen.
Original languageEnglish
Article number152
Number of pages2
JournalCritical Care
Issue number3
Publication statusPublished - 1 Jan 2010



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