Abstract
-Blocker Effects on SQTS-Mutant K+ Channels BackgroundN588K-KCNH2 and V307L-KCNQ1 mutations lead to a gain-of-function of I-Kr and I-Ks thus causing short-QT syndromes (SQT1, SQT2). Combined pharmacotherapies using K+-channel-blockers and -blockers are ef
Original language | English |
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Pages (from-to) | 1163-1171 |
Journal | Journal of Cardiovascular Electrophysiology |
Volume | 24 |
Issue number | 10 |
DOIs | |
Publication status | Published - Oct 2013 |
Keywords
- beta-adrenergic blocker
- carvedilol
- metoprolol
- potassium current
- short-QT syndrome