TY - JOUR
T1 - Diagnosis, management and impact of painful diabetic peripheral neuropathy: A patient survey in four European countries
AU - Tesfaye, S.
AU - Brill, S.
AU - Ekens, M.E.
AU - Labrador, M.M.
AU - Petersen, G.
AU - Peek, A.D.
AU - Reta, A.
AU - Ryan, D.
AU - Schaper, N.
AU - Tolle, T.
AU - Truini, A.
AU - Ziegler, D.
N1 - Funding Information:
The authors thank NexGen Healthcare Communications for their medical writing and editorial support, which was supported financially by Grünenthal GmbH. The authors would also like to thank all participants in this survey.
Funding Information:
The authors thank NexGen Healthcare Communications for their medical writing and editorial support, which was supported financially by Grünenthal GmbH. The authors would also like to thank all participants in this survey. This study was initiated and funded by Grünenthal GmbH and conducted by Hall & Partners. Not required. The survey was conducted in accordance with legal and ethical guidelines from the Market Research Society (MRS), the British Healthcare Business Intelligence Association (BHBIA), the Association of the British Pharmaceutical Industry (ABPI) Code of Practice, and the European Pharmaceutical Market Research Association (EphMRA) Code of Conduct. Ethics committee approval is not required for this type of data collection. Before completing the survey, participants were made aware of the study sponsor and gave their explicit informed consent to participate. Not commissioned; externally peer reviewed.
Publisher Copyright:
© 2023
PY - 2023/4/1
Y1 - 2023/4/1
N2 - Aims: The aim of this study was to assess patient perspectives and experiences of the impact of neuropathic pain, painful diabetic neuropathy (pDPN) diagnosis and treatment, and the patient-healthcare professional (HCP) relationship.Methods: We conducted a quantitative online survey in Germany, the Netherlands, Spain, and the UK among adults with diabetes who responded "yes" to at least four of ten questions of in the Douleur Neuropathique en 4 Questions (DN4) questionnaire.Results: Of 3626 respondents, 576 met the eligibility criteria. Daily pain was rated as moderate or severe by 79 % of respondents. Most participants reported a negative impact of their pain on sleep (74 %), mood (71 %), exercise (69 %), concentration (64 %) and daily activities (62 %), and 75 % of those in employment had missed work because of their pain in the past year. Overall, 22 % of respondents avoided discussing pain with their HCP, 50 % had not received formal pDPN diagnosis, and 56 % had not used prescribed pain medications. Although two-thirds (67 %) of respondents reported feeling satisfied or very satisfied with treatment, 82 % of these patients still experienced daily moderate or severe pain.Conclusions: Neuropathic pain in people with diabetes affects daily life and remains underdiagnosed and undertreated in clinical practice.
AB - Aims: The aim of this study was to assess patient perspectives and experiences of the impact of neuropathic pain, painful diabetic neuropathy (pDPN) diagnosis and treatment, and the patient-healthcare professional (HCP) relationship.Methods: We conducted a quantitative online survey in Germany, the Netherlands, Spain, and the UK among adults with diabetes who responded "yes" to at least four of ten questions of in the Douleur Neuropathique en 4 Questions (DN4) questionnaire.Results: Of 3626 respondents, 576 met the eligibility criteria. Daily pain was rated as moderate or severe by 79 % of respondents. Most participants reported a negative impact of their pain on sleep (74 %), mood (71 %), exercise (69 %), concentration (64 %) and daily activities (62 %), and 75 % of those in employment had missed work because of their pain in the past year. Overall, 22 % of respondents avoided discussing pain with their HCP, 50 % had not received formal pDPN diagnosis, and 56 % had not used prescribed pain medications. Although two-thirds (67 %) of respondents reported feeling satisfied or very satisfied with treatment, 82 % of these patients still experienced daily moderate or severe pain.Conclusions: Neuropathic pain in people with diabetes affects daily life and remains underdiagnosed and undertreated in clinical practice.
KW - Painful diabetic peripheral neuropathy
KW - Diabetic neuropathies
KW - Pain
KW - Diabetes complications
KW - Surveys and questionnaires
KW - POLYNEUROPATHY
KW - BURDEN
KW - CARE
KW - ILLNESS
KW - DN4
U2 - 10.1016/j.jdiacomp.2023.108417
DO - 10.1016/j.jdiacomp.2023.108417
M3 - Article
C2 - 36905720
SN - 1056-8727
VL - 37
JO - Journal of Diabetes and Its Complications
JF - Journal of Diabetes and Its Complications
IS - 4
M1 - 108417
ER -