Diabetic retinopathy in Tanzania: prevalence and risk factors at entry into a regional screening programme

Charles R. Cleland*, Matthew J. Burton, Claudette Hall, Anthony Hall, Paul Courtright, William U. Makupa, Heiko Philippin

*Corresponding author for this work

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Abstract

Objective The number of adults with diabetes in sub-Saharan Africa (SSA) is expected to almost double by 2035. This study investigated the prevalence of diabetic retinopathy (DR) and its risk factors at entry into a community-based screening programme. MethodsAll persons with diabetes screened for retinopathy at entry into a screening programme in Kilimanjaro Region, Tanzania between November 2010 and December 2014 were included. Fundus photographs were taken with a Topcon retinal camera following pupil dilation. Data were collected on BP, random blood sugar, duration of diabetes, BMI and visual acuity on entry. ResultsA total of 3187 persons were screened for DR. The prevalence of any DR was 27.9% (95%CI 26.4-29.5%) with background diabetic retinopathy (BDR), pre-proliferative diabetic retinopathy (PPDR) and proliferative diabetic retinopathy (PDR) having a prevalence of 19.1% (95% CI 17.7-20.4%), 6.0% (95%CI 5.2-6.8%) and 2.9% (95%CI 2.3-3.5%), respectively. Maculopathy was present in 16.1% (95%CI 14.8-17.4%) of participants. Multivariable logistic regression analysis for the presence of any DR found independent associations with duration of diabetes (P <0.0001), systolic BP (P <0.0001), random blood sugar (P <0.0001) and attending a government hospital diabetic clinic (P = 0.0339). ConclusionsThis study is the first to present data from a DR screening programme in SSA. The results will provide policymakers with data to aid planning of DR screening and treatment services in the African region. The study highlights the importance of managing comorbidities within DR screening programmes.
Original languageEnglish
Pages (from-to)417-426
JournalTropical Medicine & International Health
Volume21
Issue number3
DOIs
Publication statusPublished - Mar 2016

Keywords

  • diabetic retinopathy
  • screening
  • Africa

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