Detrimental Effects of an Inhaled Phosphodiesterase-4 Inhibitor on Lung Inflammation in Ventilated Preterm Lambs Exposed to Chorioamnionitis Are Dose Dependent

Matthias C. Huetten*, Markus Fehrholz, Franziska M. Konrad, Daan Ophelders, Clementine Kleintjes, Barbara Ottensmeier, Owen Brad Spiller, Kirsten Glaser, Boris W. Kramer, Steffen Kunzmann

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)396-404
Number of pages9
JournalJournal of Aerosol Medicine and Pulmonary Drug Delivery
Volume32
Issue number6
DOIs
Publication statusPublished - Dec 2019

Keywords

  • bronchopulmonary dysplasia
  • lung injury
  • mechanical ventilation of neonates
  • PDE4 inhibitors
  • prematurity
  • BRONCHOPULMONARY DYSPLASIA
  • NEBULIZED PENTOXIFYLLINE
  • PULMONARY-DISEASE
  • PDE4 INHIBITOR
  • INJURY
  • COLONIZATION
  • MECHANISMS
  • EXPRESSION
  • TOXICITY
  • INFANTS

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