Detrimental Effects of an Inhaled Phosphodiesterase-4 Inhibitor on Lung Inflammation in Ventilated Preterm Lambs Exposed to Chorioamnionitis Are Dose Dependent

Matthias C. Huetten*, Markus Fehrholz, Franziska M. Konrad, Daan Ophelders, Clementine Kleintjes, Barbara Ottensmeier, Owen Brad Spiller, Kirsten Glaser, Boris W. Kramer, Steffen Kunzmann

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1-9
Number of pages9
JournalJournal of Aerosol Medicine and Pulmonary Drug Delivery
Volume32
Issue number6
DOIs
Publication statusPublished - 1 Oct 2019

Keywords

  • bronchopulmonary dysplasia
  • lung injury
  • mechanical ventilation of neonates
  • PDE4 inhibitors
  • prematurity
  • BRONCHOPULMONARY DYSPLASIA
  • NEBULIZED PENTOXIFYLLINE
  • PULMONARY-DISEASE
  • PDE4 INHIBITOR
  • INJURY
  • COLONIZATION
  • MECHANISMS
  • EXPRESSION
  • TOXICITY
  • INFANTS

Cite this

Huetten, Matthias C. ; Fehrholz, Markus ; Konrad, Franziska M. ; Ophelders, Daan ; Kleintjes, Clementine ; Ottensmeier, Barbara ; Spiller, Owen Brad ; Glaser, Kirsten ; Kramer, Boris W. ; Kunzmann, Steffen. / Detrimental Effects of an Inhaled Phosphodiesterase-4 Inhibitor on Lung Inflammation in Ventilated Preterm Lambs Exposed to Chorioamnionitis Are Dose Dependent. In: Journal of Aerosol Medicine and Pulmonary Drug Delivery. 2019 ; Vol. 32, No. 6. pp. 1-9.
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keywords = "bronchopulmonary dysplasia, lung injury, mechanical ventilation of neonates, PDE4 inhibitors, prematurity, BRONCHOPULMONARY DYSPLASIA, NEBULIZED PENTOXIFYLLINE, PULMONARY-DISEASE, PDE4 INHIBITOR, INJURY, COLONIZATION, MECHANISMS, EXPRESSION, TOXICITY, INFANTS",
author = "Huetten, {Matthias C.} and Markus Fehrholz and Konrad, {Franziska M.} and Daan Ophelders and Clementine Kleintjes and Barbara Ottensmeier and Spiller, {Owen Brad} and Kirsten Glaser and Kramer, {Boris W.} and Steffen Kunzmann",
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Detrimental Effects of an Inhaled Phosphodiesterase-4 Inhibitor on Lung Inflammation in Ventilated Preterm Lambs Exposed to Chorioamnionitis Are Dose Dependent. / Huetten, Matthias C.; Fehrholz, Markus; Konrad, Franziska M.; Ophelders, Daan; Kleintjes, Clementine; Ottensmeier, Barbara; Spiller, Owen Brad; Glaser, Kirsten; Kramer, Boris W.; Kunzmann, Steffen.

In: Journal of Aerosol Medicine and Pulmonary Drug Delivery, Vol. 32, No. 6, 01.10.2019, p. 1-9.

Research output: Contribution to journalArticleAcademicpeer-review

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AU - Huetten, Matthias C.

AU - Fehrholz, Markus

AU - Konrad, Franziska M.

AU - Ophelders, Daan

AU - Kleintjes, Clementine

AU - Ottensmeier, Barbara

AU - Spiller, Owen Brad

AU - Glaser, Kirsten

AU - Kramer, Boris W.

AU - Kunzmann, Steffen

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KW - mechanical ventilation of neonates

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KW - prematurity

KW - BRONCHOPULMONARY DYSPLASIA

KW - NEBULIZED PENTOXIFYLLINE

KW - PULMONARY-DISEASE

KW - PDE4 INHIBITOR

KW - INJURY

KW - COLONIZATION

KW - MECHANISMS

KW - EXPRESSION

KW - TOXICITY

KW - INFANTS

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