TY - JOUR
T1 - Determinants of quality of life in family caregivers in MCI
T2 - a comparison with mild dementia
AU - Tan, Eva Y. L.
AU - Janssen, Niels
AU - Handels, Ron
AU - Ramakers, Inez H. G. B.
AU - Verhey, Frans R. J.
AU - van der Flier, Wiesje M.
AU - Melis, Rene J. F.
AU - Rikkert, Marcel G. M. Olde
AU - Schols, Jos M. G. A.
AU - de Vugt, Marjolein E.
PY - 2023/10/3
Y1 - 2023/10/3
N2 - ObjectivesThe aim of the current study was to investigate the health-related quality of life (HRQol) of the family caregiver in MCI, explore possible determinants and study possible differences with mild dementia.MethodsThis secondary data analysis included 145 persons with MCI and 154 persons with dementia and their family caregivers from two Dutch cohort studies. HRQoL was measured with the VAS of the EuroQol-5D-3L version. Regressions analyses were conducted to examine potential demographic and clinical determinants of the caregiver's HRQoL.ResultsThe mean EQ5D-VAS in family caregivers of persons with MCI was 81.1 (SD 15.7), and did not significantly differ from family caregivers in mild dementia (81.9 (SD 13.0)). In MCI, patient measurements were not significantly associated with caregiver mean EQ5D-VAS. Concerning caregiver characteristics, being a spouse and a lower educational level were associated with a lower mean EQ5D-VAS (in a multiple linear regression model: unstandardized B -8.075, p = 0.013 and unstandardized B -6.162, p = 0.037 resp.). In mild dementia, the NPI item irritability showed an association with caregiver EQ5D-VAS in bivariate linear regression analyses.ConclusionResults indicate that especially family caregiver characteristics seem to influence family caregiver HRQoL in MCI. Future research should include other potential determinants such as burden, coping strategies and relationship quality.
AB - ObjectivesThe aim of the current study was to investigate the health-related quality of life (HRQol) of the family caregiver in MCI, explore possible determinants and study possible differences with mild dementia.MethodsThis secondary data analysis included 145 persons with MCI and 154 persons with dementia and their family caregivers from two Dutch cohort studies. HRQoL was measured with the VAS of the EuroQol-5D-3L version. Regressions analyses were conducted to examine potential demographic and clinical determinants of the caregiver's HRQoL.ResultsThe mean EQ5D-VAS in family caregivers of persons with MCI was 81.1 (SD 15.7), and did not significantly differ from family caregivers in mild dementia (81.9 (SD 13.0)). In MCI, patient measurements were not significantly associated with caregiver mean EQ5D-VAS. Concerning caregiver characteristics, being a spouse and a lower educational level were associated with a lower mean EQ5D-VAS (in a multiple linear regression model: unstandardized B -8.075, p = 0.013 and unstandardized B -6.162, p = 0.037 resp.). In mild dementia, the NPI item irritability showed an association with caregiver EQ5D-VAS in bivariate linear regression analyses.ConclusionResults indicate that especially family caregiver characteristics seem to influence family caregiver HRQoL in MCI. Future research should include other potential determinants such as burden, coping strategies and relationship quality.
KW - Mild cognitive impairment
KW - dementia
KW - family caregiver
KW - quality of life
KW - EQ5D-VAS
KW - COGNITIVE IMPAIRMENT
KW - NEUROPSYCHIATRIC SYMPTOMS
KW - INFORMAL CAREGIVERS
KW - BURDEN
KW - PEOPLE
KW - INTERVENTIONS
KW - INSTRUMENT
KW - CARERS
U2 - 10.1080/13607863.2023.2220274
DO - 10.1080/13607863.2023.2220274
M3 - Article
C2 - 37310855
SN - 1360-7863
VL - 27
SP - 1983
EP - 1989
JO - Aging & Mental Health
JF - Aging & Mental Health
IS - 10
ER -