TY - JOUR
T1 - Detection of Bone Marrow Edema in the Head and Neck With Dual-Energy CT
T2 - Ready for Clinical Use?
AU - Timmer, Veronique C. M. L.
AU - van Kroonenburgh, Annemarieke M. J. L.
AU - Henneman, Wouter J. P.
AU - Vaassen, Lauretta A. A.
AU - Roele, Elise D.
AU - Kessler, Peter A. W. H.
AU - Postma, Alida A.
N1 - Funding Information:
Supported by an institutional research grant from Siemens Healthcare to the Department of Radiology of Maastricht University Medical Center.
Publisher Copyright:
© 2020 American Roentgen Ray Society.
PY - 2020/4
Y1 - 2020/4
N2 - OBJECTIVE. The aim of this study is to evaluate the ability of dual-energy CT (DECT`) to identify bone marrow edema (BME) in the head and neck region in comparison with MRI as the standard of reference.MATERIALS AND METHODS. A total of 33 patients who underwent imaging between February 2016 and February 2018 were included in this retrospective study. All patients underwent both DECT and MRI for head and neck abnormalities. Two radiologists independently visually assessed virtual noncalcium (VNCa) reconstructions with color-coded maps for the presence of BME. STIR or T2-weighted MRI reconstructions with fat suppression were used as the standard of reference for BME. Subjective quality assessment and severity of metal artifacts were scored on both imaging modalities.RESULTS. BME was detected in 18 patients on DECT compared with 20 patients on MRI. Most BME seen on DECT was located in the mandible. VNCa DECT images had a sensitivity, specificity, positive predictive value, and negative predictive value for BME of 85%, 92%, 94%, and 80% respectively, using MRI as the reference. The quality of the images was rated as excellent to moderate in 94% of the patients for VNCa DECT compared with 82% of the patients for MRI, but this difference was not statistically significant. Significantly more metal artifacts were scored on the mixed DECT images than on the MR images, but these artifacts did not interfere with diagnosis.CONCLUSION. BME detection in the head and neck region seems possible with VNCa DECT images and has the potential to provide an alternative for MRI in clinical practice.
AB - OBJECTIVE. The aim of this study is to evaluate the ability of dual-energy CT (DECT`) to identify bone marrow edema (BME) in the head and neck region in comparison with MRI as the standard of reference.MATERIALS AND METHODS. A total of 33 patients who underwent imaging between February 2016 and February 2018 were included in this retrospective study. All patients underwent both DECT and MRI for head and neck abnormalities. Two radiologists independently visually assessed virtual noncalcium (VNCa) reconstructions with color-coded maps for the presence of BME. STIR or T2-weighted MRI reconstructions with fat suppression were used as the standard of reference for BME. Subjective quality assessment and severity of metal artifacts were scored on both imaging modalities.RESULTS. BME was detected in 18 patients on DECT compared with 20 patients on MRI. Most BME seen on DECT was located in the mandible. VNCa DECT images had a sensitivity, specificity, positive predictive value, and negative predictive value for BME of 85%, 92%, 94%, and 80% respectively, using MRI as the reference. The quality of the images was rated as excellent to moderate in 94% of the patients for VNCa DECT compared with 82% of the patients for MRI, but this difference was not statistically significant. Significantly more metal artifacts were scored on the mixed DECT images than on the MR images, but these artifacts did not interfere with diagnosis.CONCLUSION. BME detection in the head and neck region seems possible with VNCa DECT images and has the potential to provide an alternative for MRI in clinical practice.
KW - bone marrow edema
KW - dual-energy CT
KW - head and neck
KW - MRI
KW - VERTEBRAL COMPRESSION FRACTURES
KW - METAL ARTIFACT REDUCTION
KW - COMPUTED-TOMOGRAPHY
KW - DIAGNOSTIC-ACCURACY
KW - ALGORITHM
KW - PATTERN
KW - SPINE
KW - HIP
U2 - 10.2214/AJR.19.21881
DO - 10.2214/AJR.19.21881
M3 - Article
C2 - 32045307
SN - 0361-803X
VL - 214
SP - 893
EP - 899
JO - American Journal of Roentgenology
JF - American Journal of Roentgenology
IS - 4
ER -