Design, synthesis, and biological evaluation of novel pyrrolidinone small-molecule Formyl peptide receptor 2 agonists

M. Maciuszek*, A. Ortega-Gomez, S.L. Maas, J. Garrido-Mesa, B. Ferraro, M. Perretti, A. Merritt, G.A.F. Nicolaes, O. Soehnlein, T.M. Chapman

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number113805
Number of pages19
JournalEuropean Journal of Medicinal Chemistry
Volume226
DOIs
Publication statusPublished - 15 Dec 2021

Keywords

  • FPR2
  • Pharmacophore
  • Agonists
  • Neutrophils
  • Resolution of inflammation
  • A(4) STABLE ANALOGS
  • SYSTEMIC DELIVERY
  • RESOLUTION
  • INFLAMMATION
  • DATABASE
  • MODEL

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