Defective deacetylation of histone 4 K12 in human oocytes is associated with advanced maternal age and chromosome misalignment

I. M. van den Berg, C. Eleveld, M. van der Hoeven, Erwin Birnie, E. A. P. Steegers, Robert-Jan H. Galjaard, J. S. E. Laven, J. H. van Doorninck

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1181-1190
JournalHuman Reproduction
Volume26
Issue number5
DOIs
Publication statusPublished - May 2011

Keywords

  • histone deacetylation
  • female meiosis
  • maternal age
  • misaligned chromosomes
  • aneuploidy

Cite this

van den Berg, I. M., Eleveld, C., van der Hoeven, M., Birnie, E., Steegers, E. A. P., Galjaard, R-J. H., Laven, J. S. E., & van Doorninck, J. H. (2011). Defective deacetylation of histone 4 K12 in human oocytes is associated with advanced maternal age and chromosome misalignment. Human Reproduction, 26(5), 1181-1190. https://doi.org/10.1093/humrep/der030