Defective deacetylation of histone 4 K12 in human oocytes is associated with advanced maternal age and chromosome misalignment

I. M. van den Berg, C. Eleveld, M. van der Hoeven, Erwin Birnie, E. A. P. Steegers, Robert-Jan H. Galjaard, J. S. E. Laven, J. H. van Doorninck*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

58 Citations (Web of Science)
Original languageEnglish
Pages (from-to)1181-1190
JournalHuman Reproduction
Issue number5
Publication statusPublished - May 2011


  • histone deacetylation
  • female meiosis
  • maternal age
  • misaligned chromosomes
  • aneuploidy

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