Daratumumab augments alloreactive natural killer cell cytotoxicity towards CD38+multiple myeloma cell lines in a biochemical context mimicking tumour microenvironment conditions

Niken M. Mahaweni, Gerard M. J. Bos, Constantine S. Mitsiades, Marcel G. J. Tilanus, Lotte Wieten

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)861-872
Number of pages12
JournalCancer Immunology Immunotherapy
Volume67
Issue number6
DOIs
Publication statusPublished - 1 Jun 2018

Keywords

  • Alloreactive NK cells
  • Multiple myeloma
  • Daratumumab
  • Tumor microenvironment
  • ADCC
  • MULTIPLE-MYELOMA
  • NK CELLS
  • SUPPRESSOR-CELLS
  • ACTIVATING RECEPTORS
  • EXPRESSION
  • HYPOXIA
  • INHIBITION
  • ANTIBODIES
  • THERAPY
  • PATHWAY

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