TY - JOUR
T1 - Cross-sectional associations between 24-hour movement behaviors and cardiometabolic health among adults with type 2 diabetes mellitus
T2 - A comparison according to weight status
AU - Willems, Iris
AU - Verbestel, Vera
AU - Dumuid, Dorothea
AU - Stanford, Tyman E
AU - Calders, Patrick
AU - Lapauw, Bruno
AU - Bogaert, Lotte
AU - Blom, Marieke T
AU - den Braver, Nicolette R
AU - van der Velde, Jeroen H P M
AU - Rutters, Femke
AU - De Craemer, Marieke
PY - 2024/3
Y1 - 2024/3
N2 - Objectives: Type 2 diabetes mellitus (T2DM) is a chronic disease associated with overweight and obesity. Evidence suggests that 24-hour movement behaviors (24 h-MBs) play a crucial role in cardiometabolic health. However, it is not yet known if 24 h-MBs differ between weight status groups among people with T2DM (PwT2DM) and how 24 h-MBs are associated with their cardiometabolic health. Design: Cross-sectional study. Methods: Cardiometabolic variables (i.e. Body Mass Index (BMI), waist circumference (WC), HbA1c, fasting glucose, triglycerides, total-cholesterol, HDL-cholesterol, LDL-cholesterol, blood pressure) and 24 h-MBs (accelerometry and sleep-diary) of 1001 PwT2DM were collected. Regression models using compositional data analysis explored differences in 24 h-MBs between weight status groups and analyzed associations with cardiometabolic variables. Results: The 24 h-MBs of PwT2DM being obese consisted of less sleep, light physical activity (LPA) and moderate to vigorous physical activity (MVPA) and more sedentary time (ST) per day as compared to PwT2DM being overweight or normal weight (p < 0.001). Regardless of weight status, the largest associations were found when reallocating 20 min a day from ST into MVPA for BMI (− 0.32 kg/m
2; [− 0.55; − 0.09], − 1.09 %), WC (− 1.44 cm, [− 2.26; − 0.62], − 1.35 %) and HDL-cholesterol (0.02 mmol/l, [0.01, 0.02], + 1.59 %), as well as from ST into LPA for triglycerides (− 0.04 mmol/l, [− 0.05; − 0.03], − 2.3 %). Moreover, these associations were different when stratifying people by short-to-average (7.7 h/night) versus long sleep (9.3 h/night) period. Conclusions: This study highlights the importance of 24 h-MBs in the cardiometabolic health of PwT2DM. Shifting time from ST and/or sleep toward LPA or MVPA might theoretically benefit cardiometabolic health among relatively inactive PwT2DM, irrespective of weight status.
AB - Objectives: Type 2 diabetes mellitus (T2DM) is a chronic disease associated with overweight and obesity. Evidence suggests that 24-hour movement behaviors (24 h-MBs) play a crucial role in cardiometabolic health. However, it is not yet known if 24 h-MBs differ between weight status groups among people with T2DM (PwT2DM) and how 24 h-MBs are associated with their cardiometabolic health. Design: Cross-sectional study. Methods: Cardiometabolic variables (i.e. Body Mass Index (BMI), waist circumference (WC), HbA1c, fasting glucose, triglycerides, total-cholesterol, HDL-cholesterol, LDL-cholesterol, blood pressure) and 24 h-MBs (accelerometry and sleep-diary) of 1001 PwT2DM were collected. Regression models using compositional data analysis explored differences in 24 h-MBs between weight status groups and analyzed associations with cardiometabolic variables. Results: The 24 h-MBs of PwT2DM being obese consisted of less sleep, light physical activity (LPA) and moderate to vigorous physical activity (MVPA) and more sedentary time (ST) per day as compared to PwT2DM being overweight or normal weight (p < 0.001). Regardless of weight status, the largest associations were found when reallocating 20 min a day from ST into MVPA for BMI (− 0.32 kg/m
2; [− 0.55; − 0.09], − 1.09 %), WC (− 1.44 cm, [− 2.26; − 0.62], − 1.35 %) and HDL-cholesterol (0.02 mmol/l, [0.01, 0.02], + 1.59 %), as well as from ST into LPA for triglycerides (− 0.04 mmol/l, [− 0.05; − 0.03], − 2.3 %). Moreover, these associations were different when stratifying people by short-to-average (7.7 h/night) versus long sleep (9.3 h/night) period. Conclusions: This study highlights the importance of 24 h-MBs in the cardiometabolic health of PwT2DM. Shifting time from ST and/or sleep toward LPA or MVPA might theoretically benefit cardiometabolic health among relatively inactive PwT2DM, irrespective of weight status.
KW - Cardiovascular diseases
KW - Obesity
KW - Overweight
KW - Physical activity
KW - Sedentary time
KW - Sleep
U2 - 10.1016/j.jsams.2023.11.010
DO - 10.1016/j.jsams.2023.11.010
M3 - Article
SN - 1440-2440
VL - 27
SP - 179
EP - 186
JO - Journal of Science and Medicine in Sport
JF - Journal of Science and Medicine in Sport
IS - 3
ER -