Corneal endothelial cell density after vitrectomy with silicone oil for complex retinal detachments

F. Goezinne, R.M. Nuijts, A.T. Liem, I.J. Lundqvist, Tos J. Berendschot, D.W. Cals, F. Hendrikse, E.C. La Heij

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

PURPOSE: To evaluate the endothelial cell density changes in eyes with silicone oil tamponade after vitrectomy for complex rhegmatogenous retinal detachment. METHODS: A prospective controlled study with 81 eyes with complex rhegmatogenous retinal detachment undergoing vitrectomy and silicone oil tamponade. Fellow eyes that fulfilled specific inclusion criteria served as controls. Endothelial cell density (in cells per square millimeter), coefficient of variance (standard deviation per mean cell area x 100), percentage of hexagonal cells, and corneal thickness were documented preoperatively and compared with values obtained at 3, 6, and 12 months postoperatively. For the purpose of the study analysis, all study eyes were divided into 5 groups, according to their lens status during the follow-up. RESULTS: High endothelial cell density loss was found in Group 3, (eyes that underwent an additional phacoemulsification procedure) and Group 4 (eyes that underwent lens and/or intraocular lens removal during the follow-up) at 12 months with a mean cell loss of 19% and 39%, respectively (P < 0.001). CONCLUSION: An intact natural or artificial lens-iris diaphragm may provide a protective barrier against corneal endothelial cell damage from long-term silicone oil tamponade.
Original languageEnglish
Pages (from-to)228-236
Number of pages9
JournalRetina-The Journal of Retinal and Vitreous Diseases
Volume34
Issue number2
DOIs
Publication statusPublished - Feb 2014

Keywords

  • silicone oil
  • vitrectomy
  • endothelial cell density
  • endothelial cell loss
  • silicone oil tamponade
  • aphakia
  • rhegmatogenous retinal detachment
  • PHAKIC INTRAOCULAR-LENS
  • ANGLE-CLOSURE GLAUCOMA
  • PARS-PLANA VITRECTOMY
  • PROLIFERATIVE VITREORETINOPATHY
  • ANTERIOR-CHAMBER
  • RISK-FACTORS
  • SPECULAR MICROSCOPY
  • FOLLOW-UP
  • IMPLANTATION
  • PHACOEMULSIFICATION

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