Collagen Degradation and Formation Are Elevated in Exacerbated COPD Compared With Stable Disease

Desiree M. Schumann, Diana Leeming, Eleni Papakonstantinou, Francesco Blasi, Konstantinos Kostikas, Wim Boersma, Renaud Louis, Branislava Milenkovic, Joachim Aerts, Jannie M. B. Sand, Emiel F. M. Wouters, Gernot Rohde, Christina Prat, Antoni Torres, Tobias Welte, Michael Tamm, Morten Karsdal, Daiana Stolz

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)798-807
Number of pages10
JournalChest
Volume154
Issue number4
DOIs
Publication statusPublished - 1 Oct 2018

Keywords

  • basement membrane
  • C1
  • C4
  • cell turnover
  • collagen
  • COPD
  • ECM
  • lamina reticularis
  • type I collagen
  • type IV collagen
  • OBSTRUCTIVE PULMONARY-DISEASE
  • BIOMARKERS
  • FIBROSIS
  • LUNG
  • CORTICOSTEROIDS
  • TURNOVER
  • PROFILE
  • ASTHMA
  • URINE

Cite this

Schumann, D. M., Leeming, D., Papakonstantinou, E., Blasi, F., Kostikas, K., Boersma, W., Louis, R., Milenkovic, B., Aerts, J., Sand, J. M. B., Wouters, E. F. M., Rohde, G., Prat, C., Torres, A., Welte, T., Tamm, M., Karsdal, M., & Stolz, D. (2018). Collagen Degradation and Formation Are Elevated in Exacerbated COPD Compared With Stable Disease. Chest, 154(4), 798-807. https://doi.org/10.1016/j.chest.2018.06.028