Over the past few decades, chronic obstructive lung disease (COPD) has considered a disease of the lungs, often caused by smoking. Nowadays, regarded as a systemic disease. Both physical effects and effects on including impaired psychological and cognitive functioning, have been demonstrated. Patients with COPD may have cognitive impairment, either or in single cognitive domains, such as information processing, concentration, memory, executive functioning, and self-control. Possible are hypoxemia, hypercapnia, exacerbations, and decreased physical Cognitive impairment in these patients may be related to structural abnormalities, such as gray-matter pathologic changes and the loss of matter integrity which can be induced by smoking. Cognitive impairment negative impact on health and daily life and may be associated with consequences for disease management programs. It is important to assess functioning in patients with COPD in order to optimize patient-oriented and to reduce personal discomfort, hospital admissions, and mortality. will summarize the current knowledge about cognitive impairment as feature of COPD. Hereby, the impact of smoking on cognitive functioning impact of cognitive impairment on smoking behaviour will be examined.
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