Clinical interaction between diabetes duration and aortic stiffness in type 2 diabetes mellitus

D. Agnoletti; A. S. Mansour; Y. Zhang; A. D. Protogerou; S. Ouerdane; J. Blacher; M. E. Safar

doi:10.1038/jhh.2016.58

Clinical interaction between diabetes duration and aortic stiffness in type 2 diabetes mellitus

D. Agnoletti, A. S. Mansour, Y. Zhang, A. D. Protogerou, S. Ouerdane, J. Blacher, M. E. Safar^*

^*Corresponding author for this work

Interne Geneeskunde

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Diabetes complications increase with disease duration. No study was performed on the relationship between aortic stiffness and diabetes duration, taking into account the respective influence of such factors on macro-and microcirculation. In total, 618 subjects with type 2 diabetes (259 men) attending the Department of Internal Medicine of Tizi Ouzou Hospital (Algeria) were studied in collaboration with Hotel-Dieu Hospital (Paris, France). Brachial blood pressure (BP), anthropometric, clinical and biological data were evaluated. Aortic stiffness was estimated by carotid-femoral pulse wave velocity (PWV). From lower to higher tertile of diabetes duration, age, BP and PWV (10.1 +/- 2.7 to 12.3 +/- 2.8 m s(-1)) increased, while diabetes control and renal function worsened (all P

Original language	English
Pages (from-to)	189-194
Number of pages	6
Journal	Journal of Human Hypertension
Volume	31
Issue number	3
DOIs	https://doi.org/10.1038/jhh.2016.58
Publication status	Published - Mar 2017

Keywords

PULSE-WAVE VELOCITY
ARTERIAL STIFFNESS
CARDIOVASCULAR-DISEASE
VASCULAR FUNCTION
MORTALITY
DISTENSIBILITY
PRESSURE
IMPACT
KIDNEY
INDEX

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10.1038/jhh.2016.58

Cite this

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title = "Clinical interaction between diabetes duration and aortic stiffness in type 2 diabetes mellitus",

abstract = "Diabetes complications increase with disease duration. No study was performed on the relationship between aortic stiffness and diabetes duration, taking into account the respective influence of such factors on macro-and microcirculation. In total, 618 subjects with type 2 diabetes (259 men) attending the Department of Internal Medicine of Tizi Ouzou Hospital (Algeria) were studied in collaboration with Hotel-Dieu Hospital (Paris, France). Brachial blood pressure (BP), anthropometric, clinical and biological data were evaluated. Aortic stiffness was estimated by carotid-femoral pulse wave velocity (PWV). From lower to higher tertile of diabetes duration, age, BP and PWV (10.1 +/- 2.7 to 12.3 +/- 2.8 m s(-1)) increased, while diabetes control and renal function worsened (all P",

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AU - Mansour, A. S.

AU - Zhang, Y.

AU - Protogerou, A. D.

AU - Ouerdane, S.

AU - Blacher, J.

AU - Safar, M. E.

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KW - ARTERIAL STIFFNESS

KW - CARDIOVASCULAR-DISEASE

KW - VASCULAR FUNCTION

KW - MORTALITY

KW - DISTENSIBILITY

KW - PRESSURE

KW - IMPACT

KW - KIDNEY

KW - INDEX

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