Clinical interaction between diabetes duration and aortic stiffness in type 2 diabetes mellitus

D. Agnoletti, A. S. Mansour, Y. Zhang, A. D. Protogerou, S. Ouerdane, J. Blacher, M. E. Safar*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

18 Citations (Web of Science)

Abstract

Diabetes complications increase with disease duration. No study was performed on the relationship between aortic stiffness and diabetes duration, taking into account the respective influence of such factors on macro-and microcirculation. In total, 618 subjects with type 2 diabetes (259 men) attending the Department of Internal Medicine of Tizi Ouzou Hospital (Algeria) were studied in collaboration with Hotel-Dieu Hospital (Paris, France). Brachial blood pressure (BP), anthropometric, clinical and biological data were evaluated. Aortic stiffness was estimated by carotid-femoral pulse wave velocity (PWV). From lower to higher tertile of diabetes duration, age, BP and PWV (10.1 +/- 2.7 to 12.3 +/- 2.8 m s(-1)) increased, while diabetes control and renal function worsened (all P

Original languageEnglish
Pages (from-to)189-194
Number of pages6
JournalJournal of Human Hypertension
Volume31
Issue number3
DOIs
Publication statusPublished - Mar 2017

Keywords

  • PULSE-WAVE VELOCITY
  • ARTERIAL STIFFNESS
  • CARDIOVASCULAR-DISEASE
  • VASCULAR FUNCTION
  • MORTALITY
  • DISTENSIBILITY
  • PRESSURE
  • IMPACT
  • KIDNEY
  • INDEX

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