Chronic airflow obstruction and ambient particulate air pollution

A.F.S. Amaral; P.G.J. Burney; J. Patel; C. Minelli; F. Mejza; D.M. Mannino; T.A.R. Seemungal; P.A. Mahesh; L.C. Lo; C. Janson; S. Juvekar; M. Denguezli; I. Harrabi; E.F.M. Wouters; H. Cherkaski; K. Mortimer; R. Jogi; E.D. Bateman; E. Fuertes; M. Al Ghobain; W. Tan; D.O. Obaseki; A. El Sony; M. Studnicka; A. Aquart-Stewart; P. Koul; H. Lawin; A.A. Nafees; O. Awopeju; G.E. Erhabor; T. Gislason; T. Welte; A. Gulsvik; R. Nielsen; L. Gnatiuc; A. Kocabas; G.B. Marks; T. Sooronbaev; B.H.M. Ngahane; C. Barbara; A.S. Buist; BOLD Collaborative Research Group

doi:10.1136/thoraxjnl-2020-216223

Chronic airflow obstruction and ambient particulate air pollution

A.F.S. Amaral^*, P.G.J. Burney, J. Patel, C. Minelli, F. Mejza, D.M. Mannino, T.A.R. Seemungal, P.A. Mahesh, L.C. Lo^*, C. Janson, S. Juvekar, M. Denguezli, I. Harrabi, E.F.M. Wouters, H. Cherkaski, K. Mortimer, R. Jogi, E.D. Bateman, E. Fuertes, M. Al GhobainW. Tan, D.O. Obaseki, A. El Sony, M. Studnicka, A. Aquart-Stewart, P. Koul, H. Lawin, A.A. Nafees, O. Awopeju, G.E. Erhabor, T. Gislason, T. Welte, A. Gulsvik, R. Nielsen, L. Gnatiuc, A. Kocabas, G.B. Marks, T. Sooronbaev, B.H.M. Ngahane, C. Barbara, A.S. Buist, BOLD Collaborative Research Group

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Smoking is the most well-established cause of chronic airflow obstruction (CAO) but particulate air pollution and poverty have also been implicated. We regressed sex-specific prevalence of CAO from 41 Burden of Obstructive Lung Disease study sites against smoking prevalence from the same study, the gross national income per capita and the local annual mean level of ambient particulate matter (PM2.5) using negative binomial regression. The prevalence of CAO was not independently associated with PM2.5 but was strongly associated with smoking and was also associated with poverty. Strengthening tobacco control and improved understanding of the link between CAO and poverty should be prioritised.

Original language	English
Pages (from-to)	1236-1241
Number of pages	6
Journal	Thorax
Volume	76
Issue number	12
DOIs	https://doi.org/10.1136/thoraxjnl-2020-216223
Publication status	Published - 1 Dec 2021

Keywords

COPD epidemiology
PREVALENCE

Access to Document

10.1136/thoraxjnl-2020-216223Licence: CC BY

Cite this

Amaral, A. F. S., Burney, P. G. J., Patel, J., Minelli, C., Mejza, F., Mannino, D. M., Seemungal, T. A. R., Mahesh, P. A., Lo, L. C., Janson, C., Juvekar, S., Denguezli, M., Harrabi, I., Wouters, E. F. M., Cherkaski, H., Mortimer, K., Jogi, R., Bateman, E. D., Fuertes, E., ... BOLD Collaborative Research Group (2021). Chronic airflow obstruction and ambient particulate air pollution. Thorax, 76(12), 1236-1241. https://doi.org/10.1136/thoraxjnl-2020-216223

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abstract = "Smoking is the most well-established cause of chronic airflow obstruction (CAO) but particulate air pollution and poverty have also been implicated. We regressed sex-specific prevalence of CAO from 41 Burden of Obstructive Lung Disease study sites against smoking prevalence from the same study, the gross national income per capita and the local annual mean level of ambient particulate matter (PM2.5) using negative binomial regression. The prevalence of CAO was not independently associated with PM2.5 but was strongly associated with smoking and was also associated with poverty. Strengthening tobacco control and improved understanding of the link between CAO and poverty should be prioritised.",

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author = "A.F.S. Amaral and P.G.J. Burney and J. Patel and C. Minelli and F. Mejza and D.M. Mannino and T.A.R. Seemungal and P.A. Mahesh and L.C. Lo and C. Janson and S. Juvekar and M. Denguezli and I. Harrabi and E.F.M. Wouters and H. Cherkaski and K. Mortimer and R. Jogi and E.D. Bateman and E. Fuertes and {Al Ghobain}, M. and W. Tan and D.O. Obaseki and {El Sony}, A. and M. Studnicka and A. Aquart-Stewart and P. Koul and H. Lawin and A.A. Nafees and O. Awopeju and G.E. Erhabor and T. Gislason and T. Welte and A. Gulsvik and R. Nielsen and L. Gnatiuc and A. Kocabas and G.B. Marks and T. Sooronbaev and B.H.M. Ngahane and C. Barbara and A.S. Buist and {BOLD Collaborative Research Group}",

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Amaral, AFS, Burney, PGJ, Patel, J, Minelli, C, Mejza, F, Mannino, DM, Seemungal, TAR, Mahesh, PA, Lo, LC, Janson, C, Juvekar, S, Denguezli, M, Harrabi, I, Wouters, EFM, Cherkaski, H, Mortimer, K, Jogi, R, Bateman, ED, Fuertes, E, Al Ghobain, M, Tan, W, Obaseki, DO, El Sony, A, Studnicka, M, Aquart-Stewart, A, Koul, P, Lawin, H, Nafees, AA, Awopeju, O, Erhabor, GE, Gislason, T, Welte, T, Gulsvik, A, Nielsen, R, Gnatiuc, L, Kocabas, A, Marks, GB, Sooronbaev, T, Ngahane, BHM, Barbara, C, Buist, AS & BOLD Collaborative Research Group 2021, 'Chronic airflow obstruction and ambient particulate air pollution', Thorax, vol. 76, no. 12, pp. 1236-1241. https://doi.org/10.1136/thoraxjnl-2020-216223

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T1 - Chronic airflow obstruction and ambient particulate air pollution

AU - Amaral, A.F.S.

AU - Burney, P.G.J.

AU - Patel, J.

AU - Minelli, C.

AU - Mejza, F.

AU - Mannino, D.M.

AU - Seemungal, T.A.R.

AU - Mahesh, P.A.

AU - Lo, L.C.

AU - Janson, C.

AU - Juvekar, S.

AU - Denguezli, M.

AU - Harrabi, I.

AU - Wouters, E.F.M.

AU - Cherkaski, H.

AU - Mortimer, K.

AU - Jogi, R.

AU - Bateman, E.D.

AU - Fuertes, E.

AU - Al Ghobain, M.

AU - Tan, W.

AU - Obaseki, D.O.

AU - El Sony, A.

AU - Studnicka, M.

AU - Aquart-Stewart, A.

AU - Koul, P.

AU - Lawin, H.

AU - Nafees, A.A.

AU - Awopeju, O.

AU - Erhabor, G.E.

AU - Gislason, T.

AU - Welte, T.

AU - Gulsvik, A.

AU - Nielsen, R.

AU - Gnatiuc, L.

AU - Kocabas, A.

AU - Marks, G.B.

AU - Sooronbaev, T.

AU - Ngahane, B.H.M.

AU - Barbara, C.

AU - Buist, A.S.

AU - BOLD Collaborative Research Group

PY - 2021/12/1

Y1 - 2021/12/1

N2 - Smoking is the most well-established cause of chronic airflow obstruction (CAO) but particulate air pollution and poverty have also been implicated. We regressed sex-specific prevalence of CAO from 41 Burden of Obstructive Lung Disease study sites against smoking prevalence from the same study, the gross national income per capita and the local annual mean level of ambient particulate matter (PM2.5) using negative binomial regression. The prevalence of CAO was not independently associated with PM2.5 but was strongly associated with smoking and was also associated with poverty. Strengthening tobacco control and improved understanding of the link between CAO and poverty should be prioritised.

AB - Smoking is the most well-established cause of chronic airflow obstruction (CAO) but particulate air pollution and poverty have also been implicated. We regressed sex-specific prevalence of CAO from 41 Burden of Obstructive Lung Disease study sites against smoking prevalence from the same study, the gross national income per capita and the local annual mean level of ambient particulate matter (PM2.5) using negative binomial regression. The prevalence of CAO was not independently associated with PM2.5 but was strongly associated with smoking and was also associated with poverty. Strengthening tobacco control and improved understanding of the link between CAO and poverty should be prioritised.

KW - COPD epidemiology

KW - PREVALENCE

U2 - 10.1136/thoraxjnl-2020-216223

DO - 10.1136/thoraxjnl-2020-216223

M3 - Article

C2 - 33975927

SN - 0040-6376

VL - 76

SP - 1236

EP - 1241

JO - Thorax

JF - Thorax

IS - 12

ER -