Bundle Branch Block and Benefit from Cardiac Resynchronization Therapy

R. Zusterzeel

Research output: ThesisDoctoral ThesisInternal

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Heart failure is a common chronic disease caused by reduced pump function. Treatment is expensive and the mortality rate is high, particularly in women. One cause is the nonsynchronous contraction of the heart muscle. This can be corrected with cardiac resynchronisation therapy (CRT) via a pacemaker. This study found that, compared to men, women had a lower threshold criterion for CRT; benefited more from CRT, including fewer symptoms and a lower mortality rate; were offered CRT less frequently than men; and were underrepresented in clinical trials with no mention of gender-specific outcomes.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Maastricht University
  • Gorgels, Antonius, Supervisor
  • Strauss, D.G., Co-Supervisor, External person
Award date20 May 2015
Place of PublicationMaastricht
Print ISBNs9789461594365
Publication statusPublished - 2015


  • women
  • cardiology
  • heart failure
  • cardiac resynchronisation therapy
  • death

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