Body mass index and chronic airflow limitation in a worldwide population-based study

Lowie E. G. W. Vanfleteren*, Bernd Lamprecht, Michael Studnicka, Bernhard Kaiser, Louisa Gnatiuc, Peter Burney, Emiel F. M. Wouters, Frits M. E. Franssen

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Nutritional status has been associated with clinical outcome in chronic airflow limitation (CAL), but epidemiological studies are scarce. We aimed to assess the relationship between body mass index (BMI) and CAL, taking into account confounding factors. 18,606 participants (49% male, 21% smokers, mean age: 55.8 +/- 11.2 years, mean BMI: 26.7 +/- 5.5 kg/m(2)) of the BOLD initiative from 26 sites in 23 countries were included. CAL was defined as post-bronchodilator forced expiratory volume in the first second/forced vital capacity <lower limit of normal. Low and obese BMI were defined as
Original languageEnglish
Pages (from-to)90-101
JournalChronic respiratory disease
Issue number2
Publication statusPublished - May 2016


  • Chronic airflow limitation
  • chronic obstructive pulmonary disease
  • body mass index
  • burden of obstructive lung disease (BOLD)

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