Purpose: To prospectively determine the screening mammography outcome at blinded and non-blinded double reading in a;biennial population based screening programme in the south of the Netherlands.
Methods: We included a consecutive series of 87,487 digital screening mammograms, obtained between July 2009 and July 2011. Screening mammograms were double read in either a blinded (2nd reader was not informed about the 1st reader's decision) or non-blinded fashion (2nd reader was informed about the 1st reader's decision). This reading strategy was alternated on a monthly basis. Women with discrepant readings between the two radiologists were always referred for further analysis. During 2 years follow-up, we collected the radiology reports, surgical correspondence and pathology reports of all referred women and interval breast cancers.
Results: Respectively 44,491 and 42,996 screens had been read either in a blinded or non-blinded fashion. Referral rate (3.3% versus 2.8%, p
Conclusion: We advocate the use of blinded double reading in order to achieve a better programme sensitivity, at the expense of an increased referral rate and false positive referral rate. (C) 2014 Elsevier Ltd. All rights reserved.
- Breast cancer
- Screening mammography
- Double reading
- Referral rate
- Positive predictive value
- FALSE-POSITIVE MAMMOGRAMS
- BREAST-CANCER MORTALITY