Bioactive and osteoinductive bone graft substitutes: Definitions, facts and myths

T. J. Blokhuis*, Chris Arts

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

100 Citations (Web of Science)


The use of artificial bone grafts has been developed over recent years and is expected to increase further, for some indications even replacing the gold standard, autograft, in trauma and reconstructive surgery. However, the effectiveness of these materials is still a subject of debate, mostly because of unclear definitions or limited market surveillance. In this overview several facts and myths regarding bone-graft substitutes are summarized.
Original languageEnglish
Pages (from-to)S26-S29
JournalInjury-International Journal of the Care of the Injured
Publication statusPublished - Sep 2011


  • Bone graft substitutes
  • Autologous bone graft
  • BMPs
  • Clacium Phospahtes
  • Allograft
  • DBM

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