Beneficial role of CD8+T-cell reconstitution after HLA-haploidentical stem cell transplantation for high-risk acute leukaemias: results from a clinico-biological EBMT registry study mostly in the T-cell-depleted setting

Attilio Bondanza; Loredana Ruggeri; Maddalena Noviello; Dirk-Jan Eikema; Chiara Bonini; Christian Chabannon; Steffie van der Werf; Anja van Biezen; Liesbeth C. de Wreede; Lara Crucitti; Luca Vago; Mara Merluzzi; Maria Speranza Massei; Hendrik Veelken; Yener Koc; Peter Bader; Bernd Gruhn; Franco Locatelli; Fabio Ciceri; Antoine Toubert; Andrea Velardi; Maria Ester Bernardo; Francesco Dazzi; Rose Ellard; Katharina Fleischhauer; Rafaella Greco; Michael Hudecek; Ulrike Koehl; Jurgen Kuball; Florent Malard; Paolo Pedrazzoli; Vanderson Rocha; Annalisa Ruggeri; Alvaro Urbano-Ispizua; Junfeng Wang; Lotte Wieten; EBMT Cell Therapy and Immunobiology Working Party

doi:10.1038/s41409-018-0351-x

Beneficial role of CD8+T-cell reconstitution after HLA-haploidentical stem cell transplantation for high-risk acute leukaemias: results from a clinico-biological EBMT registry study mostly in the T-cell-depleted setting

Attilio Bondanza^*, Loredana Ruggeri, Maddalena Noviello, Dirk-Jan Eikema, Chiara Bonini, Christian Chabannon, Steffie van der Werf, Anja van Biezen, Liesbeth C. de Wreede, Lara Crucitti, Luca Vago, Mara Merluzzi, Maria Speranza Massei, Hendrik Veelken, Yener Koc, Peter Bader, Bernd Gruhn, Franco Locatelli, Fabio Ciceri, Antoine ToubertAndrea Velardi, Maria Ester Bernardo, Francesco Dazzi, Rose Ellard, Katharina Fleischhauer, Rafaella Greco, Michael Hudecek, Ulrike Koehl, Jurgen Kuball, Florent Malard, Paolo Pedrazzoli, Vanderson Rocha, Annalisa Ruggeri, Alvaro Urbano-Ispizua, Junfeng Wang, Lotte Wieten, EBMT Cell Therapy and Immunobiology Working Party

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

5 Citations (Web of Science)

Original language	English
Pages (from-to)	867-876
Number of pages	10
Journal	Bone Marrow Transplantation
Volume	54
Issue number	6
DOIs	https://doi.org/10.1038/s41409-018-0351-x
Publication status	Published - Jun 2019

Keywords

ADULTS
BLOOD
BONE-MARROW-TRANSPLANTATION
COUNT
DISEASE
IMMUNOTHERAPY
INDEX
RECOVERY
RESPONSES
SCORE
CHILDREN

Access to Document

10.1038/s41409-018-0351-x

Cite this

Bondanza, A., Ruggeri, L., Noviello, M., Eikema, D-J., Bonini, C., Chabannon, C., van der Werf, S., van Biezen, A., de Wreede, L. C., Crucitti, L., Vago, L., Merluzzi, M., Massei, M. S., Veelken, H., Koc, Y., Bader, P., Gruhn, B., Locatelli, F., Ciceri, F., ... EBMT Cell Therapy and Immunobiology Working Party (2019). Beneficial role of CD8+T-cell reconstitution after HLA-haploidentical stem cell transplantation for high-risk acute leukaemias: results from a clinico-biological EBMT registry study mostly in the T-cell-depleted setting. Bone Marrow Transplantation, 54(6), 867-876. https://doi.org/10.1038/s41409-018-0351-x

Bondanza, Attilio ; Ruggeri, Loredana ; Noviello, Maddalena ; Eikema, Dirk-Jan ; Bonini, Chiara ; Chabannon, Christian ; van der Werf, Steffie ; van Biezen, Anja ; de Wreede, Liesbeth C. ; Crucitti, Lara ; Vago, Luca ; Merluzzi, Mara ; Massei, Maria Speranza ; Veelken, Hendrik ; Koc, Yener ; Bader, Peter ; Gruhn, Bernd ; Locatelli, Franco ; Ciceri, Fabio ; Toubert, Antoine ; Velardi, Andrea ; Bernardo, Maria Ester ; Dazzi, Francesco ; Ellard, Rose ; Fleischhauer, Katharina ; Greco, Rafaella ; Hudecek, Michael ; Koehl, Ulrike ; Kuball, Jurgen ; Malard, Florent ; Pedrazzoli, Paolo ; Rocha, Vanderson ; Ruggeri, Annalisa ; Urbano-Ispizua, Alvaro ; Wang, Junfeng ; Wieten, Lotte ; EBMT Cell Therapy and Immunobiology Working Party. / Beneficial role of CD8+T-cell reconstitution after HLA-haploidentical stem cell transplantation for high-risk acute leukaemias : results from a clinico-biological EBMT registry study mostly in the T-cell-depleted setting. In: Bone Marrow Transplantation. 2019 ; Vol. 54, No. 6. pp. 867-876.

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title = "Beneficial role of CD8+T-cell reconstitution after HLA-haploidentical stem cell transplantation for high-risk acute leukaemias: results from a clinico-biological EBMT registry study mostly in the T-cell-depleted setting",

keywords = "ADULTS, BLOOD, BONE-MARROW-TRANSPLANTATION, COUNT, DISEASE, IMMUNOTHERAPY, INDEX, RECOVERY, RESPONSES, SCORE, CHILDREN",

author = "Attilio Bondanza and Loredana Ruggeri and Maddalena Noviello and Dirk-Jan Eikema and Chiara Bonini and Christian Chabannon and {van der Werf}, Steffie and {van Biezen}, Anja and {de Wreede}, {Liesbeth C.} and Lara Crucitti and Luca Vago and Mara Merluzzi and Massei, {Maria Speranza} and Hendrik Veelken and Yener Koc and Peter Bader and Bernd Gruhn and Franco Locatelli and Fabio Ciceri and Antoine Toubert and Andrea Velardi and Bernardo, {Maria Ester} and Francesco Dazzi and Rose Ellard and Katharina Fleischhauer and Rafaella Greco and Michael Hudecek and Ulrike Koehl and Jurgen Kuball and Florent Malard and Paolo Pedrazzoli and Vanderson Rocha and Annalisa Ruggeri and Alvaro Urbano-Ispizua and Junfeng Wang and Lotte Wieten and {EBMT Cell Therapy and Immunobiology Working Party}",

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Bondanza, A, Ruggeri, L, Noviello, M, Eikema, D-J, Bonini, C, Chabannon, C, van der Werf, S, van Biezen, A, de Wreede, LC, Crucitti, L, Vago, L, Merluzzi, M, Massei, MS, Veelken, H, Koc, Y, Bader, P, Gruhn, B, Locatelli, F, Ciceri, F, Toubert, A, Velardi, A, Bernardo, ME, Dazzi, F, Ellard, R, Fleischhauer, K, Greco, R, Hudecek, M, Koehl, U, Kuball, J, Malard, F, Pedrazzoli, P, Rocha, V, Ruggeri, A, Urbano-Ispizua, A, Wang, J, Wieten, L & EBMT Cell Therapy and Immunobiology Working Party 2019, 'Beneficial role of CD8+T-cell reconstitution after HLA-haploidentical stem cell transplantation for high-risk acute leukaemias: results from a clinico-biological EBMT registry study mostly in the T-cell-depleted setting', Bone Marrow Transplantation, vol. 54, no. 6, pp. 867-876. https://doi.org/10.1038/s41409-018-0351-x

Beneficial role of CD8+T-cell reconstitution after HLA-haploidentical stem cell transplantation for high-risk acute leukaemias : results from a clinico-biological EBMT registry study mostly in the T-cell-depleted setting. / Bondanza, Attilio; Ruggeri, Loredana; Noviello, Maddalena; Eikema, Dirk-Jan; Bonini, Chiara; Chabannon, Christian; van der Werf, Steffie; van Biezen, Anja; de Wreede, Liesbeth C.; Crucitti, Lara; Vago, Luca; Merluzzi, Mara; Massei, Maria Speranza; Veelken, Hendrik; Koc, Yener; Bader, Peter; Gruhn, Bernd; Locatelli, Franco; Ciceri, Fabio; Toubert, Antoine; Velardi, Andrea; Bernardo, Maria Ester; Dazzi, Francesco; Ellard, Rose; Fleischhauer, Katharina; Greco, Rafaella; Hudecek, Michael; Koehl, Ulrike; Kuball, Jurgen; Malard, Florent; Pedrazzoli, Paolo; Rocha, Vanderson; Ruggeri, Annalisa; Urbano-Ispizua, Alvaro; Wang, Junfeng; Wieten, Lotte; EBMT Cell Therapy and Immunobiology Working Party.

In: Bone Marrow Transplantation, Vol. 54, No. 6, 06.2019, p. 867-876.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Beneficial role of CD8+T-cell reconstitution after HLA-haploidentical stem cell transplantation for high-risk acute leukaemias

T2 - results from a clinico-biological EBMT registry study mostly in the T-cell-depleted setting

AU - Bondanza, Attilio

AU - Ruggeri, Loredana

AU - Noviello, Maddalena

AU - Eikema, Dirk-Jan

AU - Bonini, Chiara

AU - Chabannon, Christian

AU - van der Werf, Steffie

AU - van Biezen, Anja

AU - de Wreede, Liesbeth C.

AU - Crucitti, Lara

AU - Vago, Luca

AU - Merluzzi, Mara

AU - Massei, Maria Speranza

AU - Veelken, Hendrik

AU - Koc, Yener

AU - Bader, Peter

AU - Gruhn, Bernd

AU - Locatelli, Franco

AU - Ciceri, Fabio

AU - Toubert, Antoine

AU - Velardi, Andrea

AU - Bernardo, Maria Ester

AU - Dazzi, Francesco

AU - Ellard, Rose

AU - Fleischhauer, Katharina

AU - Greco, Rafaella

AU - Hudecek, Michael

AU - Koehl, Ulrike

AU - Kuball, Jurgen

AU - Malard, Florent

AU - Pedrazzoli, Paolo

AU - Rocha, Vanderson

AU - Ruggeri, Annalisa

AU - Urbano-Ispizua, Alvaro

AU - Wang, Junfeng

AU - Wieten, Lotte

AU - EBMT Cell Therapy and Immunobiology Working Party

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KW - BLOOD

KW - BONE-MARROW-TRANSPLANTATION

KW - COUNT

KW - DISEASE

KW - IMMUNOTHERAPY

KW - INDEX

KW - RECOVERY

KW - RESPONSES

KW - SCORE

KW - CHILDREN

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DO - 10.1038/s41409-018-0351-x

M3 - Article

C2 - 30531916

VL - 54

SP - 867

EP - 876

JO - Bone Marrow Transplantation

JF - Bone Marrow Transplantation

SN - 0268-3369

IS - 6

ER -

Bondanza A, Ruggeri L, Noviello M, Eikema D-J, Bonini C, Chabannon C et al. Beneficial role of CD8+T-cell reconstitution after HLA-haploidentical stem cell transplantation for high-risk acute leukaemias: results from a clinico-biological EBMT registry study mostly in the T-cell-depleted setting. Bone Marrow Transplantation. 2019 Jun;54(6):867-876. https://doi.org/10.1038/s41409-018-0351-x