Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation

Rene Luijk, Haoyu Wu, Cavin K. Ward-Caviness, Eilis Hannon, Elena Carnero-Montoro, Josine L. Min, Pooja Mandaviya, Martina Muller-Nurasyid, Hailiang Mei, Silvere M. van der Maarel, Caroline Relton, Jonathan Mill, Melanie Waldenberger, Jordana T. Bell, Rick Jansen, Alexandra Zhernakova, Lude Franke, Peter A. C. 't Hoen, Dorret I. Boomsma, Cornelia M. van DuijnMarleen M. J. van Greevenbroek, Jan H. Veldink, Cisca Wijmenga, Joyce van Meurs, Lucia Daxinger, P. Eline Slagboom, Erik W. van Zwet, Bastiaan T. Heijmans, BIOS Consortium

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number3738
Number of pages9
JournalNature Communications
Volume9
DOIs
Publication statusPublished - 14 Sep 2018

Keywords

  • HUMAN GENOME
  • LINKED GENE
  • HISTONE H3
  • EXPRESSION
  • SMCHD1
  • VARIABILITY
  • OBJECTIVES
  • EPIGENOMES
  • ROTTERDAM
  • CLUSTERS
  • Humans
  • DNA Methylation/genetics
  • Male
  • Chromosomal Proteins, Non-Histone/genetics
  • Gene Expression Profiling
  • Genetic Variation
  • Female
  • Methyltransferases/genetics
  • Tripartite Motif Proteins/genetics
  • Gene Expression
  • gamma-Globins/genetics
  • DNA-Binding Proteins/genetics
  • CpG Islands
  • Ubiquitin-Protein Ligases/genetics
  • X Chromosome Inactivation/genetics

Cite this

Luijk, R., Wu, H., Ward-Caviness, C. K., Hannon, E., Carnero-Montoro, E., Min, J. L., Mandaviya, P., Muller-Nurasyid, M., Mei, H., van der Maarel, S. M., Relton, C., Mill, J., Waldenberger, M., Bell, J. T., Jansen, R., Zhernakova, A., Franke, L., 't Hoen, P. A. C., Boomsma, D. I., ... BIOS Consortium (2018). Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation. Nature Communications, 9, [3738]. https://doi.org/10.1038/s41467-018-05714-3